Aging and Neurodegeneration

Faculty

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Research Focus

This laboratory is currently involved in a wide range of studies aimed at understanding the causes of brain aging and identifying the basis by which aging promotes the development of brain pathology and brain diseases such as Alzheimer’s disease.

About this Lab

The lab has conducted nearly 40 clinical trials focused on neurodegenerative disease, having developed high performance drug screening models and basic science approaches to further research in this field. Led by Dr. Keller, lab members explore treatment options that show potential to slow or prevent the progression of Alzheimer’s disease in certain subsets of the population, with one of the major advances being the use of monoclonal antibody therapies. Recently, Dr. Keller has explored the use of Delta-9-tetrahydrocannabinol to treat dementia-related agitation in hospice-eligible patients.