Education

  • 1988 B.S. Microbiology, Louisiana State UniversityBaton Rouge, LA
  • 1990 M.S. Pathology, Louisiana State University Medical Center, New Orleans, LA
  • 1993 Ph.D. Pathology, Louisiana State University Medical Center, New Orleans, LA

     

Research Interests

Dr. Rood’s research interests are focused on measuring energy expenditure during weight gain/loss and during periods of intense exercise. She has also published work on protein metabolism during weight gain/loss. She has been funded by the Department of Defense since 1993 and directs the research program to optimize warfighter nutrition.

Departments: Clinical Chemistry, Exercise Testing, Mass Spectometry

Selected Publications

  1. 1. Heilbronn LK, de Jonge L, Frisard MI, DeLany JP, Larson-Meyer DE, Rood J, Nguyen T, Martin CK, Volaufova J, Most MM, Greenway FL, Smith SR, Deutsch WA, Williamson DA, Ravussin E; Pennington CALERIE Team. Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial. JAMA. 2006 Apr 5;295(13):1539-48. Erratum in: JAMA. 2006 Jun 7;295(21):2482. PMID: 16595757. PMCID: PMC2692623.
  2. 2. Sacks FM, Bray GA, Carey VJ, Smith SR, Ryan DH, Anton SD, McManus K, Champagne CM, Bishop LM, Laranjo N, Leboff MS, Rood JC, de Jonge L, Greenway FL, Loria CM, Obarzanek E, Williamson DA. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. N Engl J Med. 2009 Feb 26;360(9):859-73. doi: 10.1056/NEJMoa0804748. PMID: 19246357. PMCID: PMC2763382.
  3.  Lefevre M, Redman LM, Heilbronn LK, Smith JV, Martin CK, Rood JC, Greenway FL, Williamson DA, Smith SR, Ravussin E; Pennington CALERIE team. Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals. Atherosclerosis. 2009 Mar;203(1):206-13. doi: 10.1016/j.atherosclerosis.2008.05.036. Epub 2008 Jul 7. PMID: 18602635. PMCID: PMC2692631.
  4. McClung HL, Sigrist LD, Smith TJ, Karl JP, Rood JC, Young AJ, Bathalon GP. Monitoring energy intake: a hand-held personal digital assistant provides accuracy comparable to written records. J Am Diet Assoc. 2009 Jul;109(7):1241-5. doi: 10.1016/j.jada.2009.04.015. PMID: 19559143.
  5. Hermann GE, Van Meter MJ, Rood JC, Rogers RC. Proteinase-activated receptors in the nucleus of the solitary tract: evidence for glial-neural interactions in autonomic control of the stomach. J Neurosci. 2009 Jul 22;29(29):9292-300. doi: 10.1523/JNEUROSCI.6063-08.2009. PMID: 19625519. PMCID: PMC2773000.
  6. Losso JN, Holliday DL, Finley JW, Martin RJ, Rood JC, Yu Y, Greenway FL. Fenugreek bread: a treatment for diabetes mellitus. J Med Food. 2009 Oct;12(5):1046-9. doi: 10.1089/jmf.2008.0199. PMID: 19857068.
  7. Ryan DH, Johnson WD, Myers VH, Prather TL, McGlone MM, Rood J, Brantley PJ, Bray GA, Gupta AK, Broussard AP, Barootes BG, Elkins BL, Gaudin DE, Savory RL, Brock RD, Datz G, Pothakamuri SR, McKnight GT, Stenlof K, Sjöström LV. Nonsurgical weight loss for extreme obesity in primary care settings: results of the Louisiana Obese Subjects Study. Arch Intern Med. 2010 Jan 25;170(2):146-54. doi: 10.1001/archinternmed.2009.508. PMID: 20101009.
  8. Redman LM, Veldhuis JD, Rood J, Smith SR, Williamson D, Ravussin E; Pennington CALERIE Team. The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women. Aging Cell. 2010 Feb;9(1):32-9. doi: 10.1111/j.1474-9726.2009.00530.x. Epub 2009 Oct 30. PMID: 19878147. PMCID: PMC2807912.
  9. Cefalu WT, Rood J, Pinsonat P, Qin J, Sereda O, Levitan L, Anderson RA, Zhang XH, Martin JM, Martin CK, Wang ZQ, Newcomer B. Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus. Metabolism. 2010 May;59(5):755-62. doi: 10.1016/j.metabol.2009.09.023. Epub 2009 Dec 22. PMID: 20022616. PMCID: PMC4020630.
  10. Pasarica M, Rood J, Ravussin E, Schwarz JM, Smith SR, Redman LM. Reduced oxygenation in human obese adipose tissue is associated with impaired insulin suppression of lipolysis. J Clin Endocrinol Metab. 2010 Aug;95(8):4052-5. doi: 10.1210/jc.2009-2377. Epub 2010 May 13. PMID: 20466783. PMCID: PMC2913036.
  11.  Johannsen DL, Calabro MA, Stewart J, Franke W, Rood JC, Welk GJ. Accuracy of armband monitors for measuring daily energy expenditure in healthy adults. Med Sci Sports Exerc. 2010 Nov;42(11):2134-40. doi: 10.1249/MSS.0b013e3181e0b3ff. PMID: 20386334.
  12. Smith TJ, Schwarz JM, Montain SJ, Rood J, Pikosky MA, Castaneda-Sceppa C, Glickman E, Young AJ. High-protein diet maintains glucose production during exercise-induced energy deficit: a controlled trial. Nutr Metab (Lond). 2011 Apr 28;8:26. doi: 10.1186/1743-7075-8-26. PMID: 21527019. PMCID: PMC3100238.
  13. Pasiakos SM, McClung HL, McClung JP, Margolis LM, Andersen NE, Cloutier GJ, Pikosky MA, Rood JC, Fielding RA, Young AJ. Leucine-enriched essential amino acid supplementation during moderate steady state exercise enhances postexercise muscle protein synthesis. Am J Clin Nutr. 2011 Sep;94(3):809-18. doi: 10.3945/ajcn.111.017061. Epub 2011 Jul 20. PMID: 21775557.
  14. Johnson WD, Brashear MM, Gupta AK, Rood JC, Ryan DH. Incremental weight loss improves cardiometabolic risk in extremely obese adults. Am J Med. 2011 Oct;124(10):931-8. doi: 10.1016/j.amjmed.2011.04.033. PMID: 21962313.
  15. Bray GA, Smith SR, de Jonge L, Xie H, Rood J, Martin CK, Most M, Brock C, Mancuso S, Redman LM. Effect of dietary protein content on weight gain, energy expenditure, and body composition during overeating: a randomized controlled trial. JAMA. 2012 Jan 4;307(1):47-55. doi: 10.1001/jama.2011.1918. Erratum in: JAMA. 2012 Mar 14;307(10):1028. PMID: 22215165. PMCID: PMC3777747.
  16. Pasiakos SM, Karl JP, Lutz LJ, Murphy NE, Margolis LM, Rood JC, Cable SJ, Williams KW, Young AJ, McClung JP. Cardiometabolic risk in US Army recruits and the effects of basic combat training. PLoS One. 2012;7(2):e31222. doi: 10.1371/journal.pone.0031222. Epub 2012 Feb 23. PMID: 22384004. PMCID: PMC3285625.
  17. Margolis LM, Pasiakos SM, Karl JP, Rood JC, Cable SJ, Williams KW, Young AJ, McClung JP. Differential effects of military training on fat-free mass and plasma amino acid adaptations in men and women. Nutrients. 2012 Dec 18;4(12):2035-46. doi: 10.3390/nu4122035. PMID: 23250145. PMCID: PMC3546621.
  18. Margolis LM, Rood J, Champagne C, Young AJ, Castellani JW. Energy balance and body composition during US Army special forces training. Appl Physiol Nutr Metab. 2013 Apr;38(4):396-400. doi: 10.1139/apnm-2012-0323. Epub 2013 Apr 3. PMID: 23713532.
  19. Pasiakos SM, Cao JJ, Margolis LM, Sauter ER, Whigham LD, McClung JP, Rood JC, Carbone JW, Combs GF Jr, Young AJ. Effects of high-protein diets on fat-free mass and muscle protein synthesis following weight loss: a randomized controlled trial. FASEB J. 2013 Sep;27(9):3837-47. doi: 10.1096/fj.13-230227. Epub 2013 Jun 5. PMID: 23739654.
  20. Margolis LM, Crombie AP, McClung HL, McGraw SM, Rood JC, Montain SJ, Young AJ: Energy Requirements of US Army Special Operation Forces During Military Training. Nutrients. 2014 May 12;6(5):1945-55. doi:10.3390/nu6051945. PMID: 24824290. PMCID: PMC4042567.
  21. Rood JC, Schwarz J, Gettys T, Mynatt RL, Mendoza T, Johnson W, Cefalu W. Effects of Artemisia species on de novo lipogenesis in vivo. Nutrition. 2014 Jul-Aug;30(7-8 Suppl):S17-20. doi: 10.1016/j.nut.2014.03.029. Epub 2014 Apr 18. PMID: 24985100. PMCID: PMC4120075.
  22. Apolzan JW, Bray GA, Smith SR, de Jonge L, Rood J, Han H, Redman LM, Martin CK. Effects of weight gain induced by controlled overfeeding on physical activity. Am J Physiol Endocrinol Metab. 2014 Oct 7:ajpendo.00386.2014. doi: 10.1152/ajpendo.00386.2014. PMID: 25294214. PMCID: PMC4254990.
  23. Margolis LM, Murphy NE, Martini S, Spitz MG, Thrane I, McGraw SM, Blatny JM, Castellani JW, Rood JC, Young AJ, Montain SJ, Gundersen Y, Pasiakos SM. Effects of winter military training on energy balance, whole-body protein balance, muscle damage, soreness, and physical performance. Appl Physiol Nutr Metab. 2014 Dec;39(12):1395-401. doi: 10.1139/apnm-2014-0212. PMID: 25386980.
  24. Bray GA, Redman LM, de Jonge L, Covington J, Rood J, Brock C, Mancuso S, Martin CK, Smith SR. Effect of protein overfeeding on energy expenditure measured in a metabolic chamber. Am J Clin Nutr. 2015 Mar;101(3):496-505. doi: 10.3945/ajcn.114.091769. Epub 2015 Jan 14. PMID: 25733634.
  25. Zheng Y, Ceglarek U, Huang T, Li L, Rood J, Ryan D, Bray GA, Sacks FM, Schwarzfuchs D, Thiery J, Shai I. Weight-loss Diets and 2-year Changes in Circulating Amino Acids in Two Randomized Intervention Trials. Am J Clin Nutr. 2016 Feb;103(2):505-11. doi: 10.3945/ajcn.115.117689. Epub 2016 Jan 20. PMID: 26791187. PMCID: PMC4733257.