Education

  • PhD, Foods and Nutrition, Purdue University, West Lafayette, IN 
  • MS, Clinical Research, Tulane University, New Orleans, LA

Research Interests

Dr. Apolzan is a nutrition scientist whose research interests involve overseeing and managing human clinical intervention trials examining nutritional, physical activity, and body weight outcomes across the lifespan. He has significant experience in the development and oversight of clinic-based and mHealth interventions. He is the co-inventor of the FoodImage and PortionSize apps. Overall, he conducts translational research in the areas of human clinical nutrition, exercise physiology, and obesity to further reduce disease prevalence. 

Department: Clinical Nutrition and Metabolism

Selected Publications

  1. Food Insecurity and Weight Loss in an Underserved Primary Care Population: A Post Hoc Analysis of a Cluster Randomized Trial. Ann Intern Med. 2021. Epub 2021/03/09. doi: 10.7326/M20-6326. PubMed PMID: 33683931.
  2. Hochsmann C, Dorling JL, Martin CK, Newton RL, Jr., Apolzan JW, Myers CA, Denstel KD, Mire EF, Johnson WD, Zhang D, Arnold CL, Davis TC, Fonseca V, Lavie CJ, Price-Haywood EG, Katzmarzyk PT, Group PR. Effects of a 2-Year Primary Care Lifestyle Intervention on Cardiometabolic Risk Factors: A Cluster-Randomized Trial. Circulation. 2021;143(12):1202-14. Epub 2021/02/10. doi: 10.1161/CIRCULATIONAHA.120.051328. PubMed PMID: 33557578; PMCID: PMC7987882.
  3. Staiano AE, Shanley JR, Kihm H, Hawkins KR, Self-Brown S, Hochsmann C, Osborne MC, LeBlanc MM, Apolzan JW, Martin CK. Digital Tools to Support Family-Based Weight Management for Children: Mixed Methods Pilot and Feasibility Study. JMIR Pediatr Parent. 2021;4(1):e24714. Epub 2021/01/08. doi: 10.2196/24714. PubMed PMID: 33410760; PMCID: PMC7819774.
  4. Allaire BT, Tjaden AH, Venditti EM, Apolzan JW, Dabelea D, Delahanty LM, Edelstein SL, Hoskin MA, Temple KA, Wylie-Rosett J, Jaacks LM, Group DPPR. Diet quality, weight loss, and diabetes incidence in the Diabetes Prevention Program (DPP). BMC Nutr. 2020;6(1):74. Epub 2020/12/16. doi: 10.1186/s40795-020-00400-4. PubMed PMID: 33317629; PMCID: PMC7737274.
  5. Unick JL, Walkup MP, Miller ME, Apolzan JW, Brubaker PH, Coday M, Hill JO, Jakicic JM, Middelbeek RJW, West D, Wing RR, Look ARG. Early Physical Activity Adoption Predicts Longer-Term Physical Activity Among Individuals Inactive at Baseline. J Phys Act Health. 2020:1-8. Epub 2020/11/06. doi: 10.1123/jpah.2020-0114. PubMed PMID: 33152692.
  6. Flanagan EW, Altazan AD, Comardelle NR, Gilmore LA, Apolzan JW, St Romain J, Hardee JC, Puyau RS, Mayet CL, Beyl RA, Barlow SA, Bounds SS, Olson KN, Kennedy BM, Hsia DS, Redman LM. The Design of a Randomized Clinical Trial to Evaluate a Pragmatic and Scalable eHealth Intervention for the Management of Gestational Weight Gain in Low-Income Women: Protocol for the SmartMoms in WIC Trial. JMIR Res Protoc. 2020;9(9):e18211. Epub 2020/09/11. doi: 10.2196/18211. PubMed PMID: 32909954; PMCID: PMC7516677.
  7. Katzmarzyk PT, Martin CK, Newton RL, Jr., Apolzan JW, Arnold CL, Davis TC, Price-Haywood EG, Denstel KD, Mire EF, Thethi TK, Brantley PJ, Johnson WD, Fonseca V, Gugel J, Kennedy KB, Lavie CJ, Sarpong DF, Springgate B. Weight Loss in Underserved Patients - A Cluster-Randomized Trial. N Engl J Med. 2020;383(10):909-18. Epub 2020/09/03. doi: 10.1056/NEJMoa2007448. PubMed PMID: 32877581.
  8. Dorling JL, Ravussin E, Redman LM, Bhapkar M, Huffman KM, Racette SB, Das SK, Apolzan JW, Kraus WE, Hochsmann C, Martin CK, Group CPS. Effect of 2 years of calorie restriction on liver biomarkers: results from the CALERIE phase 2 randomized controlled trial. Eur J Nutr. 2020. Epub 2020/08/18. doi: 10.1007/s00394-020-02361-7. PubMed PMID: 32803412.
  9. Qi D, Apolzan JW, Li R, Roe BE. Unpacking the Decline in Food Waste Measured in Chinese Households from 1991 to 2009. Resour Conserv Recycl. 2020;160. Epub 2020/07/15. doi: 10.1016/j.resconrec.2020.104893. PubMed PMID: 32661454; PMCID: PMC7357877.
  10. Roe BE, Qi D, Beyl RA, Neubig KE, Martin CK, Apolzan JW. The Validity, Time Burden, and User Satisfaction of the FoodImage Smartphone App for Food Waste Measurement Versus Diaries: A Randomized Crossover Trial. Resour Conserv Recycl. 2020;160. Epub 2020/08/11. doi: 10.1016/j.resconrec.2020.104858. PubMed PMID: 32773964; PMCID: PMC7409719.
  11. Fearnbach SN, Johannsen NM, Myers CA, Apolzan JW, Johnson WD, Earnest CP, Rood JC, Tudor-Locke C, Harris MN, Church TS, Martin CK. Adaptations to exercise in compensators and noncompensators in the E-MECHANIC Trial. J Appl Physiol (1985). 2020;129(2):317-24. Epub 2020/07/17. doi: 10.1152/japplphysiol.00826.2019. PubMed PMID: 32673160.
  12. Apolzan JW, Beyl RA, Martin CK, Greenway FL, White U. The Effects of Alcohol Consumption on Cardiometabolic Health Outcomes Following Weight Loss in Premenopausal Women with Obesity: A Pilot Randomized Controlled Trial. Int J Environ Res Public Health. 2020;17(15). Epub 2020/07/29. doi: 10.3390/ijerph17155302. PubMed PMID: 32717926.
  13. Hochsmann C, Dorling JL, Apolzan JW, Johannsen NM, Hsia DS, Martin CK. Baseline Habitual Physical Activity Predicts Weight Loss, Weight Compensation, and Energy Intake During Aerobic Exercise. Obesity (Silver Spring). 2020;28(5):882-92. Epub 2020/03/08. doi: 10.1002/oby.22766. PubMed PMID: 32144895; PMCID: PMC7180105.
  14. Dorling JL, Das SK, Racette SB, Apolzan JW, Zhang D, Pieper CF, Martin CK, Group CS. Changes in body weight, adherence, and appetite during 2 years of calorie restriction: the CALERIE 2 randomized clinical trial. Eur J Clin Nutr. 2020;74(8):1210-20. Epub 2020/03/08. doi: 10.1038/s41430-020-0593-8. PubMed PMID: 32144378; PMCID: PMC7415503.
  15. Dorling JL, Church TS, Myers CA, Hochsmann C, White UA, Hsia DS, Martin CK, Apolzan JW. Racial Variations in Appetite-Related Hormones, Appetite, and Laboratory-Based Energy Intake from the E-MECHANIC Randomized Clinical Trial. Nutrients. 2019;11(9). Epub 2019/08/31. doi: 10.3390/nu11092018. PubMed PMID: 31466276.
  16. Dorling J, Bhapkar M, Das SK, Racette SB, Apolzan JW, Fearnbach SN, Redman LM, Myers CA, Stewart TM, Martin CK, Group CS. Change in self-efficacy, eating behaviors and food cravings during two years of calorie restriction in humans without obesity. Appetite. 2019:104397. Epub 2019/08/10. doi: 10.1016/j.appet.2019.104397. PubMed PMID: 31398376.
  17. Myers CA, Martin CK, Newton RL, Jr., Apolzan JW, Arnold CL, Davis TC, Price-Haywood EG, Katzmarzyk PT. Cardiovascular Health, Adiposity, and Food Insecurity in an Underserved Population. Nutrients. 2019;11(6). Epub 2019/06/30. doi: 10.3390/nu11061376. PubMed PMID: 31248113; PMCID: PMC6628173.
  18. Hawkins KR, Apolzan JW, Staiano AE, Shanley JR, Martin CK. Efficacy of a Home-Based Parent Training-Focused Weight Management Intervention for Preschool Children: The DRIVE Randomized Controlled Pilot Trial. J Nutr Educ Behav. 2019;51(6):740-8. Epub 2019/06/11. doi: 10.1016/j.jneb.2019.04.002. PubMed PMID: 31178009.
  19. Martin CK, Johnson WD, Myers CA, Apolzan JW, Earnest CP, Thomas DM, Rood JC, Johannsen NM, Tudor-Locke C, Harris M, Hsia DS, Church TS. Effect of different doses of supervised exercise on food intake, metabolism, and non-exercise physical activity: The E-MECHANIC randomized controlled trial. Am J Clin Nutr. 2019;110(3):583-92. Epub 2019/06/07. doi: 10.1093/ajcn/nqz054. PubMed PMID: 31172175; PMCID: PMC6735935.
  20. Apolzan JW, Venditti EM, Edelstein SL, Knowler WC, Dabelea D, Boyko EJ, Pi-Sunyer X, Kalyani RR, Franks PW, Srikanthan P, Gadde KM, Diabetes Prevention Program Research G. Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study. Ann Intern Med. 2019;170(10):682-90. Epub 2019/04/23. doi: 10.7326/M18-1605. PubMed PMID: 31009939; PMCID: PMC6829283.
  21. Harville EW, Apolzan JW, Bazzano LA. Maternal Pre-Pregnancy Cardiovascular Risk Factors and Offspring and Grandoffspring Health: Bogalusa Daughters. Int J Environ Res Public Health. 2018;16(1). Epub 2018/12/24. doi: 10.3390/ijerph16010015. PubMed PMID: 30577626. *Featured Article.
  22. Hawkins KR, Burton JH, Apolzan JW, Thomson JL, Williamson DA, Martin CK. Efficacy of a school-based obesity prevention intervention at reducing added sugar and sodium in children's school lunches: the LA Health randomized controlled trial. Int J Obes (Lond). 2018;42(11):1845-52. Epub 2018/09/27. doi: 10.1038/s41366-018-0214-y. PubMed PMID: 30254362; PMCID: PMC6237630.
  23. Katzmarzyk PT, Martin CK, Newton RL, Jr., Apolzan JW, Arnold CL, Davis TC, Denstel KD, Mire EF, Thethi TK, Brantley PJ, et al. Promoting Successful Weight Loss in Primary Care in Louisiana (PROPEL): Rationale, design and baseline characteristics. Contemp Clin Trials 2018;67:1-10. doi: 10.1016/j.cct.2018.02.002. PMID: 29408562.
  24. Sarzynski MA, Ruiz-Ramie JJ, Barber JL, Slentz CA, Apolzan JW, McGarrah RW, Harris MN, Church TS, Borja MS, He Y, et al. Effects of Increasing Exercise Intensity and Dose on Multiple Measures of HDL (High-Density Lipoprotein) Function. Arterioscler Thromb Vasc Biol 2018;38(4):943-52. doi: 10.1161/ATVBAHA.117.310307. PMID: 29437573.
  25. Roe BECO, Apolzan JWCO, Qi DCO, Allen HR, Martin CKCO. Plate waste of adults in the United States measured in free-living conditions. PLoS One 2018;13(2):e0191813. PMID: 29444094. COContributed equally to this work with: Brian E. Roe, John W. Apolzan, Danyi Qi, Corby K. Martin
  26. King JL, Fearnbach SN, Ramakrishnapillai S, Shankpal P, Geiselman PJ, Martin CK, Murray KB, Hicks JL, McClernon FJ, Apolzan JW, Carmichael OT. Perceptual Characterization of the Macronutrient Picture System (MaPS) for Food Image fMRI. Front Psychol 2018;9:17. doi: 10.3389/fpsyg.2018.00017. PMID: 29434559.
  27. Redman LM, Gilmore LA, Breaux J, Thomas DM, Elkind-Hirsch K, Stewart T, Hsia DS, Burton J, Apolzan JW, Cain LE, Altazan AD, Ragusa S, Brady H, Davis A, Tilford JM, Sutton EF, Martin CK. Effectiveness of SmartMoms, a Novel eHealth Intervention for Management of Gestational Weight Gain: Randomized Controlled Pilot Trial. JMIR Mhealth Uhealth. 2017 Sep 13;5(9):e133. doi: 10.2196/mhealth.8228. PubMed PMID: 28903892; PubMed Central PMCID: PMC5617906.
  28. Nicklas T, Saab R, Islam NG, Wong W, Butte N, Schulin R, Liu Y, Apolzan JW, Myers CA, Martin CK. Validity of the Remote Food Photography Method Against Doubly Labeled Water Among Minority Preschoolers. Obesity (Silver Spring). 2017 Sep;25(9):1633-1638. doi: 10.1002/oby.21931. Epub 2017 Jul 31. PubMed PMID: 28758370; PubMed Central PMCID: PMC5573622.
  29. Nicklas T, Islam NG, Saab R, Schulin R, Liu Y, Butte NF, Apolzan JW, Myers CA, Martin CK. Validity of a Digital Diet Estimation Method for Use with Preschool Children. J Acad Nutr Diet. 2017 Jun 18. pii: S2212-2672(17)30452-5. doi: 10.1016/j.jand.2017.05.005. [Epub ahead of print] PubMed PMID: 28637631; PubMed Central PMCID: PMC5735022.
  30. Apolzan JW, Myers CA, Champagne CM, Beyl RA, Raynor HA, Anton SA, Williamson DA, Sacks FM, Bray GA, Martin CK. Frequency of Consuming Foods Predicts Changes in Cravings for Those Foods During Weight Loss: The POUNDS Lost Study. Obesity (Silver Spring). 2017 Aug;25(8):1343-1348. doi: 10.1002/oby.21895. Epub 2017 Jun 15. PubMed PMID: 28618170; PubMed Central PMCID: PMC5529244.
  31. Thomas DM, Paynter J, Peterson CM, Heymsfield SB, Nduati A, Apolzan JW, Martin CK. A new universal dynamic model to describe eating rate and cumulative intake curves. Am J Clin Nutr. 2017 Feb;105(2):323-331. doi: 10.3945/ajcn.115.127811. Epub 2017 Jan 11. PubMed PMID: 28077377; PubMed Central PMCID: PMC5267295.
  32. Peterson CM, Apolzan JW, Wright C, Martin CK. Video chat technology to remotely quantify dietary, supplement and medication adherence in clinical trials. Br J Nutr. 2016 Nov;116(9):1646-1655. Epub 2016 Oct 18. PubMed PMID: 27753427; PubMed Central PMCID: PMC5282970.
  33. Altazan AD, Gilmore LA, Burton JH, Ragusa SA, Apolzan JW, Martin CK, Redman LM. Development and Application of the Remote Food Photography Method to Measure Food Intake in Exclusively Milk Fed Infants: A Laboratory-Based Study. PLoS One. 2016 Sep 29;11(9):e0163833. doi: 10.1371/journal.pone.0163833. eCollection 2016. PubMed PMID: 27684949; PubMed Central PMCID: PMC5042558.
  34. Correa JB, Apolzan JW, Shepard DN, Heil DP, Rood JC, Martin CK. Evaluation of the ability of three physical activity monitors to predict weight change and estimate energy expenditure. Appl Physiol Nutr Metab. 2016 Jul;41(7):758-66. doi: 10.1139/apnm-2015-0461. Epub 2016 Mar 14. PubMed PMID: 27270210; PubMed Central PMCID: PMC4936932.
  35. Martin CK, Gilmore LA, Apolzan JW, Myers CA, Thomas DM, Redman LM. Smartloss: A Personalized Mobile Health Intervention for Weight Management and Health Promotion. JMIR Mhealth Uhealth. 2016 Mar 16;4(1):e18. doi: 10.2196/mhealth.5027. PubMed PMID: 26983937; PubMed Central PMCID: PMC4834738.
  36. Apolzan JW, Myers CA, Cowley AD, Brady H, Hsia DS, Stewart TM, Redman LM, Martin CK. Examination of the reliability and validity of the Mindful Eating Questionnaire in pregnant women. Appetite. 2016 May 1;100:142-51. doi: 10.1016/j.appet.2016.02.025. Epub 2016 Feb 12. PubMed PMID: 26879222; PubMed Central PMCID: PMC4814227.
  37. Harris RB, Apolzan JW. Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats. Physiol Behav. 2015 Jan;138:208-18. doi: 10.1016/j.physbeh.2014.09.016. Epub 2014 Nov 6. PubMed PMID: 25446204; PubMed Central PMCID: PMC4400807.
  38. Apolzan JW, Bray GA, Smith SR, de Jonge L, Rood J, Han H, Redman LM, Martin CK. Effects of weight gain induced by controlled overfeeding on physical activity. Am J Physiol Endocrinol Metab. 2014 Dec 1;307(11):E1030-7. doi: 10.1152/ajpendo.00386.2014. Epub 2014 Oct 7. PubMed PMID: 25294214; PubMed Central PMCID: PMC4254990. * APS Select Article.
  39. Apolzan JW, Bray GA, Hamilton MT, Zderic TW, Han H, Champagne CM, Shepard D, Martin CK. Short-term overeating results in incomplete energy intake compensation regardless of energy density or macronutrient composition. Obesity (Silver Spring). 2014 Jan;22(1):119-30. doi: 10.1002/oby.20587. Epub 2013 Sep 10. PubMed PMID: 23913807; PubMed Central PMCID: PMC3873377.
  40. Apolzan JW, Harris RBS. Rapid onset and reversal of peripheral and central leptin resistance in rats offered chow, sucrose solution, and lard. Appetite. 2013 Jan;60(1):65-73. doi: 10.1016/j.appet.2012.09.020. Epub 2012 Sep 26. PubMed PMID: 23022555; PubMed Central PMCID: PMC3996830.
  41. Harris RB, Apolzan JW. Changes in glucose tolerance and leptin responsiveness of rats offered a choice of lard, sucrose, and chow. Am J Physiol Regul Integr Comp Physiol. 2012 Jun;302(11):R1327-39. doi: 10.1152/ajpregu.00477.2011. Epub 2012 Apr 11. PubMed PMID: 22496363; PubMed Central PMCID: PMC3378343.
  42. Apolzan JW, Harris RB. Differential effects of chow and purified diet on the consumption of sucrose solution and lard and the development of obesity. Physiol Behav. 2012 Jan 18;105(2):325-31. doi: 10.1016/j.physbeh.2011.08.023. Epub 2011 Aug 26. PubMed PMID: 21893075; PubMed Central PMCID: PMC3225510.
  43. Weaver CM, Campbell WW, Teegarden D, Craig BA, Martin BR, Singh R, Braun MM, Apolzan JW, Hannon TS, Schoeller DA, DiMeglio LA, Hickey Y, Peacock M. Calcium, dairy products, and energy balance in overweight adolescents: a controlled trial. Am J Clin Nutr. 2011 Nov;94(5):1163-70. doi: 10.3945/ajcn.110.010264. Epub 2011 Sep 14. PubMed PMID: 21918216; PubMed Central PMCID: PMC3192471.
  44. Apolzan JW, Leidy HJ, Mattes RD, Campbell WW. Effects of food form on food intake and postprandial appetite sensations, glucose and endocrine responses, and energy expenditure in resistance trained v. sedentary older adults. Br J Nutr. 2011 Oct;106(7):1107-16. doi: 10.1017/S0007114511001310. Epub 2011 Apr 15. PubMed PMID: 21492495; PubMed Central PMCID: PMC3885865.
  45. Conley TB, Apolzan JW, Leidy HJ, Greaves KA, Lim E, Campbell WW. Effect of food form on postprandial plasma amino acid concentrations in older adults. Br J Nutr. 2011 Jul;106(2):203-7. doi: 10.1017/S0007114511000419. PubMed PMID: 21554804; PubMed Central PMCID: PMC4554489.
  46. Leidy HJ, Apolzan JW, Mattes RD, Campbell WW. Food form and portion size affect postprandial appetite sensations and hormonal responses in healthy, nonobese, older adults. Obesity (Silver Spring). 2010 Feb;18(2):293-9. doi: 10.1038/oby.2009.217. Epub 2009 Jul 23. PubMed PMID: 19629055; PubMed Central PMCID: PMC4297632.Campbell
  47. WW, Haub MD, Wolfe RR, Ferrando AA, Sullivan DH, Apolzan JW, Iglay HB. Resistance training preserves fat-free mass without impacting changes in protein metabolism after weight loss in older women. Obesity (Silver Spring). 2009 Jul;17(7):1332-9. doi: 10.1038/oby.2009.2. Epub 2009 Feb 26. PubMed PMID: 19247271; PubMed Central PMCID: PMC4299870.
  48. Iglay HB, Apolzan JW, Gerrard DE, Eash JK, Anderson JC, Campbell WW. Moderately increased protein intake predominately from egg sources does not influence whole body, regional, or muscle composition responses to resistance training in older people. J Nutr Health Aging. 2009 Feb;13(2):108-14. PubMed PMID: 19214338.
  49. Apolzan JW, Flynn MG, McFarlin BK, Campbell WW. Age and physical activity status effects on appetite and mood state in older humans. Appl Physiol Nutr Metab. 2009 Apr;34(2):203-11. doi: 10.1139/H08-150. PubMed PMID: 19370051; PubMed Central PMCID: PMC4306339.
  50. Stull AJ, Apolzan JW, Thalacker-Mercer AE, Iglay HB, Campbell WW. Liquid and solid meal replacement products differentially affect postprandial appetite and food intake in older adults. J Am Diet Assoc. 2008 Jul;108(7):1226-30. doi: 10.1016/j.jada.2008.04.014. PubMed PMID: 18589034; PubMed Central PMCID: PMC2556245.
  51. Iglay HB, Thyfault JP, Apolzan JW, Campbell WW. Resistance training and dietary protein: effects on glucose tolerance and contents of skeletal muscle insulin signaling proteins in older persons. Am J Clin Nutr. 2007 Apr;85(4):1005-13. PubMed PMID: 17413099.
  52. Apolzan JW, Carnell NS, Mattes RD, Campbell WW. Inadequate dietary protein increases hunger and desire to eat in younger and older men. J Nutr. 2007 Jun;137(6):1478-82. PubMed PMID: 17513410; PubMed Central PMCID: PMC225945 

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