Education

  • Postdoc, Pennington Biomedical Research Center, 2020, T32 Botanicals & Metabolic Syndrome
  • PhD, Louisiana State University, 2017, Exercise Physiology
  • MS, Northeastern University , 2007, Clinical Exercise Physiology
  • BS, Louisiana State University, 2005, Kinesiology

 

Research Interests

Dr. Allerton is a PhD-trained exercise physiologist with advanced expertise in skeletal muscle, adipose tissue, and vascular physiology and metabolism. His research centers on uncovering the molecular and metabolic mechanisms underlying exercise intolerance. Dr. Allerton focuses on identifying novel pathways contributing to skeletal muscle and vascular dysfunction in heart failure with preserved ejection fraction (HFpEF). Using both preclinical models and clinical cohorts, his team investigates new therapeutic strategies to improve exercise capacity and physical function in individuals with obesity and heart failure.

Department: Vascular Metabolism

Selected Publications

  1. Quiriarte H, Noland RC, Stampley JE, Davis G, Li Z, Cho E, Kim Y, Doiron J, Spielmann G, Ghosh S, Shah SJ, Irving BA, Lefer DJ, Allerton TD. Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF. JACC Basic Transl Sci. 2024 Dec;9(12):1409-1425. doi: 10.1016/j.jacbts.2024.07.009. eCollection 2024 Dec. PubMed PMID: 39822600; PubMed Central PMCID: PMC11733766. 

  2. Quiriarte H, Cho E, Kim Y, Doiron JE, Davis G, Stampley J, Noland RC, Li Z, Shah SJ, Irving BA, Spielmann G, Lefer DJ, Allerton TD. Impact of Voluntary Exercise on Systemic Inflammation in a 2- Hit Model of Heart Failure With Preserved Ejection Fraction. J Am Heart Assoc. 2025 Feb 18;14(4):e038789. doi: 10.1161/JAHA.124.038789. Epub 2025 Feb 8. PubMed PMID: 39921506; PubMed Central PMCID: PMC12074699.

  3. Vincellette CM, Losso J, Early K, Spielmann G, Irving BA, Allerton TD. Supplemental Watermelon Juice Attenuates Acute Hyperglycemia-Induced Macro-and Microvascular Dysfunction in Healthy Adults. J Nutr. 2021 Nov 2;151(11):3450-3458. doi: 10.1093/jn/nxab279. PubMed PMID: 34510203; PubMed Central PMCID: PMC8562079.

  4. Allerton TD, Savoie JJ, Fitch MD, Hellerstein MK, Stephens JM, White U. Exercise reduced the formation of new adipocytes in the adipose tissue of mice in vivo. PLoS One. 2021;16(1):e0244804. doi: 10.1371/journal.pone.0244804. eCollection 2021. 

  5. Allerton TD, Kowalski GM, Stampley J, Irving BA, Lighton JRB, Floyd ZE, Stephens JM. An Ethanolic Extract of Artemisia dracunculus L. Enhances the Metabolic Benefits of Exercise in Diet-induced Obese Mice. Med Sci Sports Exerc. 2020 Oct 22;. doi: 10.1249/MSS.0000000000002516. [Epub ahead of print] PubMed PMID: 33105388

  6. Fuller, S.; Yu, Y.; Allerton, T.D.; Mendoza, T.; Ribnicky, D.M.; Floyd, Z.E. Adaptive Fat Oxidation Is Coupled with Increased Lipid Storage in Adipose Tissue of Female Mice Fed High Dietary Fat and Sucrose. Nutrients 2020, 12, 2233.

  7. Allerton TD, Kowalski G, Hang H. and Stephen J. Dynamic Glucose Disposal is Driven by Reduced Endogenous Glucose Production in Response to Voluntary Wheel Running: A Stable Isotope Approach. Am J Physiol Endocrinol Metab. 2020 Apr 28;. doi: 10.1152/ajpendo.00450.2019. [Epub ahead of print] PubMed PMID: 32343613; PubMed Central PMCID: PMC7468781

  8. Allerton TD, Irving BA, Spielmann G, Primeaux S, Landin D, Nelson A, Johannsen NM. Metabolic flexibility is impaired in response to acute exercise in the young offspring of mothers with type 2 diabetes. Physiol Rep. 2019 Sep; 7(17):e14189. doi: 10.14814/phy2.14189.

  9. Langer HT, Mossakowski AA, Baar K, Alcazar J, Martin-Rincon M, Alegre LM, Ara I, Calbet JAL, Hinkley JM, Coen PM, Irving BA, Allerton TD, Nair S, Lima RM, Rey-López JP, Scott D, Daly RM, Ebeling PR, Hayes A, Tessier AJ, Chevalier S, Yates BA, Brown LR, Storer TW, Westcott WL, Nifli AP, Musci RV, Konopka AR, Hamilton KL, Hepple RT. Commentaries on Viewpoint: Rejuvenation of the term sarcopenia. J Appl Physiol (1985). 2019 Jan 1;126(1):257-262. doi: 10.1152/japplphysiol.00816.2018.

  10. Allerton TD, Proctor DN, Stephens JM, Dugas TR, Spielmann G, Irving BA. l-Citrulline Supplementation: Impact on Cardiometabolic Health. Nutrients. 2018 Jul 19;10(7). doi: 10.3390/nu10070921. Review. PubMed PMID: 30029482; PubMed Central PMCID: PMC6073798.

NCBI Bibliography