John Kirwan, MSc, PhD, FACSM

George A. Bray, Jr. Endowed Super Chair in Nutrition
Professor
Executive Director

Department/Laboratory:

Phone:
(225) 763-2513
 
Fax:
(225) 763-0935
Send E-mail 
 

EDUCATION

1980 – Bachelor of Arts in Exercise Biochemistry, University of Limerick, Castletroy, Ireland

1984 – Master of Science in Exercise Biochemistry, University of Massachusetts, Amherst, MA

1987 – Doctor of Philosophy in Human Bioenergetics, Ball State University, Muncie, IN

RESEARCH INTERESTS

Our primary interest is to investigate the role of insulin resistance as an underlying cause of chronic disease, including obesity, type 2 diabetes, non-alcoholic steatohepatitis, asthma, and chronic kidney failure. We employ lifestyle, pharmacological, and surgical interventions to identify key regulatory pathways associated with disease progression, with the goal of identifying novel therapeutic targets capable of altering the treatment and management of chronic conditions.

SELECTED PUBLICATIONS

1: Kirwan JP, Münzberg H, Berthoud HR. Mechanisms Responsible for Metabolic Improvements of Bariatric Surgeries. Diabetes. 2018 Jun;67(6):1043-1044. doi: 10.2337/dbi18-0011. PubMed PMID: 29784652; PubMed Central PMCID: PMC5961412.


2: Cooper L, Ryan CG, Ells LJ, Hamilton S, Atkinson G, Cooper K, Johnson MI, Kirwan JP, Martin D. Weight loss interventions for adults with overweight/obesity and chronic musculoskeletal pain: a mixed methods systematic review. Obes Rev. 2018 Jul;19(7):989-1007. doi: 10.1111/obr.12686. Epub 2018 May 20. Review. PubMed
PMID: 29781096.


3: Fealy CE, Nieuwoudt S, Foucher JA, Scelsi AR, Malin SK, Pagadala M, Cruz LA, Li M, Rocco M, Burguera B, Kirwan JP. Functional high-intensity exercise training ameliorates insulin resistance and cardiometabolic risk factors in type 2
diabetes. Exp Physiol. 2018 Jul;103(7):985-994. doi: 10.1113/EP086844. PubMed PMID: 29766601; PubMed Central PMCID: PMC6026040.


4: Costales AB, Patil D, Mulya A, Kirwan JP, Michener CM. 2-Octylcyanoacrylate for the prevention of anastomotic leak. J Surg Res. 2018 Jun;226:166-172. doi: 10.1016/j.jss.2018.01.026. Epub 2018 Feb 22. PubMed PMID: 29661283.


5: Sacks J, Mulya A, Fealy CE, Huang H, Mosinski JD, Pagadala MR, Shimizu H, Batayyah E, Schauer PR, Brethauer SA, Kirwan JP. Effect of Roux-en-Y gastric bypass on liver mitochondrial dynamics in a rat model of obesity. Physiol Rep. 2018 Feb;6(4). doi: 10.14814/phy2.13600. PubMed PMID: 29464885; PubMed Central
PMCID: PMC5820430.


6: Malin SK, Kullman EL, Scelsi AR, Haus JM, Filion J, Pagadala MR, Godin JP, Kochhar S, Ross AB, Kirwan JP. A whole-grain diet reduces peripheral insulin resistance and improves glucose kinetics in obese adults: A randomized-controlled trial. Metabolism. 2018 May;82:111-117. doi: 10.1016/j.metabol.2017.12.011. Epub 2018 Jan 3. PubMed PMID: 29305946; PubMed Central PMCID: PMC5930046.


7: Hsieh PN, Zhou G, Yuan Y, Zhang R, Prosdocimo DA, Sangwung P, Borton AH, Boriushkin E, Hamik A, Fujioka H, Fealy CE, Kirwan JP, Peters M, Lu Y, Liao X, Ramírez-Bergeron D, Feng Z, Jain MK. A conserved KLF-autophagy pathway modulates nematode lifespan and mammalian age-associated vascular dysfunction. Nat Commun.
2017 Oct 13;8(1):914. doi: 10.1038/s41467-017-00899-5. PubMed PMID: 29030550; PubMed Central PMCID: PMC5640649.


8: Parker BM, Wu J, You J, Barnes DS, Yerian L, Kirwan JP, Schauer PR, Sessler DI. Reversal of fibrosis in patients with nonalcoholic steatohepatosis after gastric bypass surgery. BMC Obes. 2017 Sep 12;4:32. doi: 10.1186/s40608-017-0168-y. eCollection 2017. PubMed PMID: 28919979; PubMed Central PMCID: PMC5596497.


9: Nieuwoudt S, Mulya A, Fealy CE, Martelli E, Dasarathy S, Naga Prasad SV, Kirwan JP. In vitro contraction protects against palmitate-induced insulin resistance in C2C12 myotubes. Am J Physiol Cell Physiol. 2017 Nov 1;313(5):C575-C583. doi: 10.1152/ajpcell.00123.2017. Epub 2017 Aug 23. PubMed PMID: 28835436; PubMed Central PMCID: PMC5792169.


10: Miranda ER, Somal VS, Mey JT, Blackburn BK, Wang E, Farabi S, Karstoft K, Fealy CE, Kashyap S, Kirwan JP, Quinn L, Solomon TPJ, Haus JM. Circulating soluble RAGE isoforms are attenuated in obese, impaired-glucose-tolerant individuals and are associated with the development of type 2 diabetes. Am J Physiol Endocrinol Metab. 2017 Dec 1;313(6):E631-E640. doi:
10.1152/ajpendo.00146.2017. Epub 2017 Aug 15. PubMed PMID: 28811295; PubMed Central PMCID: PMC5814601.


11: Kirwan JP, Sacks J, Nieuwoudt S. The essential role of exercise in the management of type 2 diabetes. Cleve Clin J Med. 2017 Jul;84(7 Suppl 1):S15-S21. doi: 10.3949/ccjm.84.s1.03. Review. PubMed PMID: 28708479; PubMed Central PMCID: PMC5846677.


12: Nieuwoudt S, Fealy CE, Foucher JA, Scelsi AR, Malin SK, Pagadala M, Rocco M, Burguera B, Kirwan JP. Functional high-intensity training improves pancreatic ß-cell function in adults with type 2 diabetes. Am J Physiol Endocrinol Metab.
2017 Sep 1;313(3):E314-E320. doi: 10.1152/ajpendo.00407.2016. Epub 2017 May 16. PubMed PMID: 28512155; PubMed Central PMCID: PMC5625086.


13: Mulya A, Haus JM, Solomon TP, Kelly KR, Malin SK, Rocco M, Barkoukis H, Kirwan JP. Exercise training-induced improvement in skeletal muscle PGC-1a-mediated fat metabolism is independent of dietary glycemic index. Obesity (Silver Spring). 2017 Apr;25(4):721-729. doi: 10.1002/oby.21799. PubMed PMID:
28349667; PubMed Central PMCID: PMC5373498.


14: Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Aminian A, Brethauer SA, Navaneethan SD, Singh RP, Pothier CE, Nissen SE, Kashyap SR; STAMPEDE Investigators. Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes. N Engl J Med. 2017 Feb 16;376(7):641-651. doi: 10.1056/NEJMoa1600869. PubMed PMID: 28199805; PubMed Central PMCID: PMC5451258.


15: Heresi GA, Malin SK, Barnes JW, Tian L, Kirwan JP, Dweik RA. Abnormal Glucose Metabolism and High-Energy Expenditure in Idiopathic Pulmonary Arterial Hypertension. Ann Am Thorac Soc. 2017 Feb;14(2):190-199. doi: 10.1513/AnnalsATS.201608-605OC. PubMed PMID: 27922752; PubMed Central PMCID: PMC5427733.


16: Kirwan JP, Malin SK, Scelsi AR, Kullman EL, Navaneethan SD, Pagadala MR, Haus JM, Filion J, Godin JP, Kochhar S, Ross AB. A Whole-Grain Diet Reduces Cardiovascular Risk Factors in Overweight and Obese Adults: A Randomized Controlled Trial. J Nutr. 2016 Nov;146(11):2244-2251. Epub 2016 Oct 19. PubMed
PMID: 27798329; PubMed Central PMCID: PMC5086786.


17: Mahmoud AM, Szczurek MR, Blackburn BK, Mey JT, Chen Z, Robinson AT, Bian JT, Unterman TG, Minshall RD, Brown MD, Kirwan JP, Phillips SA, Haus JM. Hyperinsulinemia augments endothelin-1 protein expression and impairs vasodilation of human skeletal muscle arterioles. Physiol Rep. 2016 Aug;4(16).
pii: e12895. Epub 2016 Aug 22. PubMed PMID: 27796268; PubMed Central PMCID: PMC5002909.


18: Hulman A, Simmons RK, Vistisen D, Tabák AG, Dekker JM, Alssema M, Rutters F, Koopman AD, Solomon TP, Kirwan JP, Hansen T, Jonsson A, Gjesing AP, Eiberg H, Astrup A, Pedersen O, Sørensen TI, Witte DR, Færch K. Heterogeneity in glucose
response curves during an oral glucose tolerance test and associated cardiometabolic risk. Endocrine. 2017 Feb;55(2):427-434. doi: 10.1007/s12020-016-1126-z. Epub 2016 Oct 3. PubMed PMID: 27699707.


19: Mocanu AO, Mulya A, Huang H, Dan O, Schauer PR, Dinischiotu A, Brethauer SA, Kirwan JP. Effect of Roux-en-Y Gastric Bypass on the NLRP3 Inflammasome in Pancreatic Islets from Zucker Diabetic Fatty Rats. Obes Surg. 2016 Dec;26(12):3076-3081. PubMed PMID: 27654903; PubMed Central PMCID: PMC5121054.


20: Cooper L, Ryan C, Ells LJ, Hamilton S, Atkinson G, Cooper K, Johnson MI, Kirwan JP, Martin D. Weight-loss interventions for overweight/obese adults with chronic musculoskeletal pain: a mixed methods systematic review protocol. JBI Database System Rev Implement Rep. 2016 May;14(5):57-67. doi:
10.11124/JBISRIR-2016-002725. Review. PubMed PMID: 27532463; PubMed Central PMCID: PMC5206660.


21: Mulya A, Kirwan JP. Brown and Beige Adipose Tissue: Therapy for Obesity and Its Comorbidities? Endocrinol Metab Clin North Am. 2016 Sep;45(3):605-21. doi: 10.1016/j.ecl.2016.04.010. Review. PubMed PMID: 27519133; PubMed Central PMCID: PMC5206678.


22: Kirwan JP, Aminian A, Kashyap SR, Burguera B, Brethauer SA, Schauer PR. Bariatric Surgery in Obese Patients With Type 1 Diabetes. Diabetes Care. 2016 Jun;39(6):941-8. doi: 10.2337/dc15-2732. Review. PubMed PMID: 27222552.


23: Froylich D, Corcelles R, Daigle CR, Kirwan JP, Brethauer SA, Schauer PR. The effect of pregnancy before and/or after bariatric surgery on weight loss. Surg Obes Relat Dis. 2016 Mar-Apr;12(3):596-599. doi: 10.1016/j.soard.2015.09.005. Epub 2015 Sep 24. PubMed PMID: 27174246.


24: Mosinski JD, Kirwan JP. Longer-Term Physiological and Metabolic Effects of Gastric Bypass Surgery. Curr Diab Rep. 2016 Jun;16(6):50. doi: 10.1007/s11892-016-0747-1. Review. PubMed PMID: 27091444; PubMed Central PMCID: PMC5206659.


25: Kullman EL, Kelly KR, Haus JM, Fealy CE, Scelsi AR, Pagadala MR, Flask CA, McCullough AJ, Kirwan JP. Short-term aerobic exercise training improves gut peptide regulation in nonalcoholic fatty liver disease. J Appl Physiol (1985).
2016 May 15;120(10):1159-64. doi: 10.1152/japplphysiol.00693.2015. Epub 2016 Mar
31. PubMed PMID: 27032902; PubMed Central PMCID: PMC4867318.


26: Navaneethan SD, Schold JD, Arrigain S, Kirwan JP, Nally JV Jr. Body mass index and causes of death in chronic kidney disease. Kidney Int. 2016 Mar;89(3):675-82. doi: 10.1016/j.kint.2015.12.002. Epub 2016 Jan 12. PubMed PMID:
26880461; PubMed Central PMCID: PMC4757850.


27: Ross AB, Svelander C, Savolainen OI, Lind MV, Kirwan JP, Breton I, Godin JP, Sandberg AS. A high-throughput method for liquid chromatography-tandem mass spectrometry determination of plasma alkylresorcinols, biomarkers of whole grain wheat and rye intake. Anal Biochem. 2016 Apr 15;499:1-7. doi: 10.1016/j.ab.2015.12.023. Epub 2016 Jan 28. PubMed PMID: 26827992.


28: Mosinski JD, Pagadala MR, Mulya A, Huang H, Dan O, Shimizu H, Batayyah E, Pai RK, Schauer PR, Brethauer SA, Kirwan JP. Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress. Acta Physiol (Oxf). 2016 Jun;217(2):141-51. doi: 10.1111/apha.12640. Epub 2015 Dec 29. PubMed PMID: 26663034; PubMed Central PMCID: PMC5221503.


29: Nock NL, Owusu C, Flocke S, Krejci SA, Kullman EL, Austin K, Bennett B, Cerne S, Harmon C, Moore H, Vargo M, Hergenroeder P, Malone H, Rocco M, Tracy R, Lazarus HM, Kirwan JP, Heyman E, Berger NA. A Community-Based Exercise and
Support Group Program Improves Quality of Life in African-American Breast Cancer Survivors: A Quantitative and Qualitative Analysis. Int J Sports Exerc Med. 2015;1(3). pii: 020. Epub 2015 Sep 5. PubMed PMID: 26640827; PubMed Central PMCID: PMC4667740.


30: Navaneethan SD, Fealy CE, Scelsi AC, Arrigain S, Malin SK, Kirwan JP. A Trial of Lifestyle Modification on Cardiopulmonary, Inflammatory, and Metabolic Effects among Obese with Chronic Kidney Disease. Am J Nephrol. 2015;42(4):274-81. doi: 10.1159/000441155. Epub 2015 Oct 24. PubMed PMID: 26495987; PubMed Central PMCID: PMC4711270.


31: Mocanu AO, Mulya A, Huang H, Dan O, Shimizu H, Batayyah E, Brethauer SA, Dinischiotu A, Kirwan JP. Effect of Roux-en-Y Gastric Bypass on the NLRP3 Inflammasome in Adipose Tissue from Obese Rats. PLoS One. 2015 Oct 5;10(10):e0139764. doi: 10.1371/journal.pone.0139764. eCollection 2015. PubMed PMID: 26437377; PubMed Central PMCID: PMC4593548.


32: Maghrabi AH, Wolski K, Abood B, Licata A, Pothier C, Bhatt DL, Nissen S, Brethauer SA, Kirwan JP, Schauer PR, Kashyap SR. Two-year outcomes on bone density and fracture incidence in patients with T2DM randomized to bariatric surgery versus intensive medical therapy. Obesity (Silver Spring). 2015 Dec;23(12):2344-8. doi: 10.1002/oby.21150. Epub 2015 Jul 20. PubMed PMID: 26193177; PubMed Central PMCID: PMC4701611.


33: Aminian A, Jamal M, Augustin T, Corcelles R, Kirwan JP, Schauer PR, Brethauer SA. Failed Surgical Weight Loss Does Not Necessarily Mean Failed Metabolic Effects. Diabetes Technol Ther. 2015 Oct;17(10):682-4. doi: 10.1089/dia.2015.0064. Epub 2015 Jul 15. PubMed PMID: 26177379; PubMed Central PMCID: PMC4808286.


34: Kasumov T, Li L, Li M, Gulshan K, Kirwan JP, Liu X, Previs S, Willard B, Smith JD, McCullough A. Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis. PLoS One. 2015 May 20;10(5):e0126910. doi: 10.1371/journal.pone.0126910. eCollection 2015. PubMed PMID: 25993337; PubMed Central PMCID: PMC4439060.


35: Kasumov T, Solomon TP, Hwang C, Huang H, Haus JM, Zhang R, Kirwan JP. Improved insulin sensitivity after exercise training is linked to reduced plasma C14:0 ceramide in obesity and type 2 diabetes. Obesity (Silver Spring). 2015 Jul;23(7):1414-21. doi: 10.1002/oby.21117. Epub 2015 May 12. PubMed PMID: 25966363; PubMed Central PMCID: PMC4482773.


36: Solomon TP, Malin SK, Karstoft K, Knudsen SH, Haus JM, Laye MJ, Kirwan JP. Association between cardiorespiratory fitness and the determinants of glycemic control across the entire glucose tolerance continuum. Diabetes Care. 2015 May;38(5):921-9. doi: 10.2337/dc14-2813. Epub 2015 Mar 17. PubMed PMID: 25784661; PubMed Central PMCID: PMC4407752.


37: Malin SK, Kirwan JP, Sia CL, González F. Pancreatic ß-cell dysfunction in polycystic ovary syndrome: role of hyperglycemia-induced nuclear factor-?B activation and systemic inflammation. Am J Physiol Endocrinol Metab. 2015 May
1;308(9):E770-7. doi: 10.1152/ajpendo.00510.2014. Epub 2015 Feb 24. PubMed PMID: 25714674; PubMed Central PMCID: PMC4420895.


38: Abola MV, Thompson CL, Chen Z, Chak A, Berger NA, Kirwan JP, Li L. Serum levels of retinol-binding protein 4 and risk of colon adenoma. Endocr RelatCancer. 2015 Apr;22(2):L1-4. doi: 10.1530/ERC-14-0429. PubMed PMID: 25712946; PubMed Central PMCID: PMC4342782.


39: Khanna V, Malin SK, Bena J, Abood B, Pothier CE, Bhatt DL, Nissen S, Watanabe R, Brethauer SA, Schauer PR, Kirwan JP, Kashyap SR. Adults with long-duration type 2 diabetes have blunted glycemic and ß-cell function improvements after
bariatric surgery. Obesity (Silver Spring). 2015 Mar;23(3):523-6. doi: 10.1002/oby.21021. Epub 2015 Feb 3. PubMed PMID: 25651277; PubMed Central PMCID: PMC4340772.


40: Aminian A, Zelisko A, Kirwan JP, Brethauer SA, Schauer PR. Exploring the impact of bariatric surgery on high density lipoprotein. Surg Obes Relat Dis. 2015 Jan-Feb;11(1):238-47. doi: 10.1016/j.soard.2014.07.017. Epub 2014 Aug 11. Review. PubMed PMID: 25547050.


41: Navaneethan SD, Malin SK, Arrigain S, Kashyap SR, Kirwan JP, Schauer PR. Bariatric surgery, kidney function, insulin resistance, and adipokines in patients with decreased GFR: a cohort study. Am J Kidney Dis. 2015 Feb;65(2):345-7. doi: 10.1053/j.ajkd.2014.09.018. Epub 2014 Nov 18. PubMed PMID: 25458664; PubMed Central PMCID: PMC4469901.


42: Aminian A, Brethauer SA, Kirwan JP, Kashyap SR, Burguera B, Schauer PR. How safe is metabolic/diabetes surgery? Diabetes Obes Metab. 2015 Feb;17(2):198-201. doi: 10.1111/dom.12405. Epub 2014 Nov 19. PubMed PMID: 25352176.


43: Kirwan JP, Brethauer SA, Aminian A, Rosenthal RJ, Kashyap SR, Schauer PR. Response to comments on Brethauer et al. Bariatric surgery improves the metabolic profile of morbidly obese patients with type 1 diabetes. Diabetes care
2014;37:e51-e52. Diabetes Care. 2014 Nov;37(11):e251. doi: 10.2337/dc14-1769. PubMed PMID: 25342846.


44: Plow MA, Moore S, Husni ME, Kirwan JP. A systematic review of behavioural techniques used in nutrition and weight loss interventions among adults with mobility-impairing neurological and musculoskeletal conditions. Obes Rev. 2014
Dec;15(12):945-56. doi: 10.1111/obr.12223. Epub 2014 Sep 30. Review. PubMed PMID: 25266576; PubMed Central PMCID: PMC4321818.


45: Aminian A, Brethauer SA, Daigle CR, Kirwan JP, Burguera B, Kashyap SR, Schauer PR. Outcomes of bariatric surgery in type 2 diabetic patients with diminished pancreatic secretory reserve. Acta Diabetol. 2014 Dec;51(6):1077-9.
doi: 10.1007/s00592-014-0642-7. Epub 2014 Sep 27. PubMed PMID: 25260725.


46: Solomon TP, Malin SK, Karstoft K, Knudsen SH, Haus JM, Laye MJ, Pedersen M, Pedersen BK, Kirwan JP. Determining pancreatic ß-cell compensation for changing insulin sensitivity using an oral glucose tolerance test. Am J Physiol Endocrinol Metab. 2014 Nov 1;307(9):E822-9. doi: 10.1152/ajpendo.00269.2014. Epub 2014 Sep 2. PubMed PMID: 25184989; PubMed Central PMCID: PMC4216951.


47: Malin SK, Kashyap SR, Hammel J, Miyazaki Y, DeFronzo RA, Kirwan JP. Adjusting glucose-stimulated insulin secretion for adipose insulin resistance: an index of ß-cell function in obese adults. Diabetes Care. 2014 Nov;37(11):2940-6. doi: 10.2337/dc13-3011. Epub 2014 Aug 19. PubMed PMID: 25139885; PubMed Central PMCID:
PMC4207203.


48: Nock NL, Dimitropoulos A, Rao SM, Flask CA, Schluchter M, Zanotti KM, Rose PG, Kirwan JP, Alberts J. Rationale and design of REWARD (revving-up exercise for sustained weight loss by altering neurological reward and drive): a randomized
trial in obese endometrial cancer survivors. Contemp Clin Trials. 2014 Nov;39(2):236-45. doi: 10.1016/j.cct.2014.08.008. Epub 2014 Aug 17. PubMed PMID: 25139726; PubMed Central PMCID: PMC4294324.


49: Malin SK, Bena J, Abood B, Pothier CE, Bhatt DL, Nissen S, Brethauer SA, Schauer PR, Kirwan JP, Kashyap SR. Attenuated improvements in adiponectin and fat loss characterize type 2 diabetes non-remission status after bariatric surgery.
Diabetes Obes Metab. 2014 Dec;16(12):1230-8. doi: 10.1111/dom.12376. Epub 2014 Sep 14. PubMed PMID: 25132119; PubMed Central PMCID: PMC4227926.


50: Yogi-Morren D, Galioto R, Strandjord SE, Kennedy L, Manroa P, Kirwan JP, Kashyap S, Gunstad J. Duration of type 2 diabetes and very low density lipoprotein levels are associated with cognitive dysfunction in metabolic
syndrome. Cardiovasc Psychiatry Neurol. 2014;2014:656341. doi: 10.1155/2014/656341. Epub 2014 Jun 25. PubMed PMID: 25057411; PubMed Central
PMCID: PMC4095647.


51: Navaneethan SD, Kirwan JP, Arrigain S, Schold JD. Adiposity measures, lean body mass, physical activity and mortality: NHANES 1999-2004. BMC Nephrol. 2014
Jul 8;15:108. doi: 10.1186/1471-2369-15-108. PubMed PMID: 25005601; PubMed Central PMCID: PMC4099406.


52: González F, Kirwan JP, Rote NS, Minium J. Evidence of mononuclear cell preactivation in the fasting state in polycystic ovary syndrome. Am J Obstet Gynecol. 2014 Dec;211(6):635.e1-7. doi: 10.1016/j.ajog.2014.06.044. Epub 2014 Jun
20. PubMed PMID: 24956549; PubMed Central PMCID: PMC4253610.


53: Malin SK, Navaneethan SD, Mulya A, Huang H, Kirwan JP. Exercise-induced lowering of chemerin is associated with reduced cardiometabolic risk and
glucose-stimulated insulin secretion in older adults. J Nutr Health Aging. 2014;18(6):608-15. doi: 10.1007/s12603-014-0459-7. PubMed PMID: 24950152; PubMed Central PMCID: PMC4697740.


54: Fealy CE, Mulya A, Lai N, Kirwan JP. Exercise training decreases activation of the mitochondrial fission protein dynamin-related protein-1 in insulin-resistant human skeletal muscle. J Appl Physiol (1985). 2014 Aug 1;117(3):239-45. doi: 10.1152/japplphysiol.01064.2013. Epub 2014 Jun 19. PubMed PMID: 24947026; PubMed Central PMCID: PMC4122691.


55: Aminian A, Daigle CR, Romero-Talamás H, Kashyap SR, Kirwan JP, Brethauer SA, Schauer PR. Risk prediction of complications of metabolic syndrome before and 6 years after gastric bypass. Surg Obes Relat Dis. 2014 Jul-Aug;10(4):576-82. doi: 10.1016/j.soard.2014.01.025. Epub 2014 Jan 29. PubMed PMID: 24837561.


56: Ryan CG, McDonough S, Kirwan JP, Leveille S, Martin DJ. Authors' reply to comment by Grant et al. Eur J Pain. 2014 Jul;18(6):895. doi: 10.1002/ejp.518. PubMed PMID: 24807297.


57: Nock NL, Owusu C, Kullman EL, Austin K, Roth B, Cerne S, Harmon C, Moore H, Vargo M, Hergenroeder P, Malone H, Rocco M, Tracy R, Lazarus HM, Kirwan JP, Heyman E, Berger NA. A Community-Based Exercise and Support Group Program in
African-American Breast Cancer Survivors (ABCs). J Phys Ther Health Promot. 2013 Dec 1;1(1):15-24. PubMed PMID: 24707505; PubMed Central PMCID: PMC3975605.


58: Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Brethauer SA, Navaneethan SD, Aminian A, Pothier CE, Kim ES, Nissen SE, Kashyap SR; STAMPEDE Investigators. Bariatric surgery versus intensive medical therapy for diabetes--3-year outcomes.
N Engl J Med. 2014 May 22;370(21):2002-13. doi: 10.1056/NEJMoa1401329. Epub 2014 Mar 31. PubMed PMID: 24679060; PubMed Central PMCID: PMC5451259.


59: Malin SK, del Rincon JP, Huang H, Kirwan JP. Exercise-induced lowering of fetuin-A may increase hepatic insulin sensitivity. Med Sci Sports Exerc. 2014 Nov;46(11):2085-90. doi: 10.1249/MSS.0000000000000338. PubMed PMID: 24637346;
PubMed Central PMCID: PMC4640446.


60: Aminian A, Brethauer SA, Kashyap SR, Kirwan JP, Schauer PR. DiaRem score: external validation. Lancet Diabetes Endocrinol. 2014 Jan;2(1):12-3. doi: 10.1016/S2213-8587(13)70202-X. Epub 2013 Dec 12. PubMed PMID: 24622660. ^ top