Frank L. Greenway, M.D.

Professor--Chief Medical Officer

Department/Laboratory:
Phone:
(225) 763-2578
Fax:
(225) 763-3022
Send E-mail

EDUCATION

B.A. Stanford University, Stanford CA, 1966
M.D., University of California, Los Angeles, CA, 1970
Internal Medicine, Endocrinology/Metabolism, Harbor-UCLA Medical Center, Torrance CA, 1975

RESEARCH INTERESTS

Dr. Greenway's area of interest is developing obesity treatments including diets, herbal supplements, medical foods, devices, obesity surgery and obesity drug development. His laboratory uses human fat cells in culture to discover food components with pharmacological properties for using food as medicine. He directs the outpatient research clinic.

SELECTED PUBLICATIONS

Lee MK, Kim SG, Watkins E, Moon MK, Rhee SY, Frias JP, Chung CH, Lee SH, Block B, Cha BS, Park HK, Kim BJ, Greenway F. A novel non-PPARgamma insulin sensitizer: MLR-1023 clinicalproof-of-concept in type 2 diabetes mellitus. J Diabetes Complications. 2020 May;34(5):107555. doi:
10.1016/j.jdiacomp.2020.107555. Epub 2020 Feb 2 J Diabetes Complications. 2020. PMID: 32019723

Rebello CJ, Greenway FL, Lau FH, Lin Y, Stephens JM, Johnson WD, Coulter AA. Naringenin Promotes Thermogenic Gene Expression in Human White Adipose Tissue. Obesity (Silver Spring). 2019 Jan;27(1):103-111. doi: 10.1002/oby.22352. Epub 2018 Dec 2. Obesity (Silver Spring). 2019. PMID: 30506905

Greenway FL, Aronne LJ, Raben A, Astrup A, Apovian CM, Hill JO, Kaplan LM, Fujioka K, Matejkova E, Svacina S, Luzi L, Gnessi L, Navas-Carretero S, Alfredo Martinez J, Still CD, Sannino A, Saponaro C, Demitri C, Urban LE, Leider H, Chiquette E, Ron ES, Zohar Y, Heshmati HM. A Randomized, Double-Blind, Placebo-Controlled Study of Gelesis100: A Novel Nonsystemic Oral Hydrogel for Weight Loss. Obesity (Silver Spring). 2019 Feb;27(2):205-216. doi: 10.1002/oby.22347. Epub 2018 Nov 13.Obesity (Silver Spring). 2019. PMID: 30421844

Losso JN, Finley JW, Karki N, Liu AG, Prudente A, Tipton R, Yu Y, Greenway FL.Losso JN, et al. Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. Am J Ther. 2018 Mar/Apr;25(2):e194-e201. doi: 10.1097/MJT.0000000000000584.Am J Ther. 2018. PMID: 28901958

Rebello CJ, Nikonova EV, Zhou S, Aronne LJ, Fujioka K, Garvey WT, Smith SR, Coulter AA, Greenway FL. Effect of Lorcaserin Alone and in Combination with Phentermine on Food Cravings After 12-Week Treatment: A Randomized Substudy. Obesity (Silver Spring). 2018 Feb;26(2):332-339. doi: 10.1002/oby.22094.Obesity (Silver Spring). 2018. PMID: 29363287

le Roux CW, Astrup A, Fujioka K, Greenway F, Lau DCW, Van Gaal L, Ortiz RV, Wilding JPH, Skjøth TV, Manning LS, Pi-Sunyer X; SCALE Obesity Prediabetes NN8022-1839 Study Group. 3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial.
Lancet. 2017 Apr 8;389(10077):1399-1409. doi: 10.1016/S0140-6736(17)30069-7. Epub 2017 Feb 23.Lancet. 2017. PMID: 28237263

Look AHEAD Research Group (Appendix A), Greenway FL. Severe hypoglycemia in the Look AHEAD Trial. J Diabetes Complications. 2016 Jul;30(5):935-43. doi: 10.1016/j.jdiacomp.2016.03.016. Epub 2016 Mar 17. PMID: 27114389

Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M, Lau DC, le Roux CW, Violante Ortiz R, Jensen CB, Wilding JP; SCALE Obesity and Prediabetes NN8022-1839 Study Group. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. N Engl J Med. 2015;2;373(1):11-22.

Tam CS, Redman LM, Greenway F, LeBlanc KA, Haussmann MG, Ravussin E. Energy metabolic adaptation and cardiometablic improvements one year after gastric bypass, sleeve gastrectomy and gastric band. J Clin Endocrinol Metab. 2016;101(10):3755-67.

Marinos G, Eliades C, Raman Muthusamy V, Greenway F. Weight loss and improved quality of life with a nonsurgical endoscopic treatment for obesity: clinical results from a 3- and 6-month study. Surg Obes Relat Dis. 2014;10(5):929-34.

Liu AG, Most MM, Brashear MM, Johnson WD, Cefalu WT, Greenway FL. Reducing the glycemic index or carbohydrate content of mixed meals reduces posprandial glycemia and insulinemia over the entire day but does not affect satiety. Diabetes Care. 2012;35(8):1633-7.

Twiner EM, Liu Z, Gimble J, Yu Y, Greenway F. Pharmacokinetic pilot study of the antiangiogenic activity of standardized platycodi radix. Adv Ther. 2011;28(10):857-65.

Greenway FL, Fujioka K, Plodkowski RA, Mudalair S, Guttadauria M, Erickson J, Kim DD, Dunayevich E; COR-1 Study Group. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-1): a multicenere, randomized, double-blind, placebo-controlled, phase III trial. Lancet 2010;376(9741):595-605.
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