Education

  • PhD, Central Drug Research Institute, University of Lucknow, Lucknow, India, 2003, Botany/Molecular Biology
  • MSc, Botany, University of Delhi, Delhi, India, 1998
  • BSc, Botany, University of Delhi, Delhi, India, 1996

Curriculum Vitae

Research Interests

Dr. Singh has an broad interest in obesity and related disorders. She primarily focuses on the mechanistic role of adipose tissue, adipokines, sleep, and sleep disorders in the development of hypertension, insulin resistance, and cardiovascular diseases. She leads a hypothesis-driven translational research program which utilizes unique in-vitro models and tissue samples from well characterized, comprehensive, cross-sectional, and longitudinal human studies. As director of the Sleep and Cardiometabolic Health lab, Dr. Singh and her team are examining the impact of sleep on nutrition and physical activity towards cardiometabolic health. Building on prior studies showing that shortened sleep duration has detrimental effects on metabolism, the lab is currently examining behavioral strategies that can be leveraged when increasing sleep duration is not successful. The lab also continues to explore approaches to reduce cardiovascular risk in populations with sleep disorders including sleep apnea and insomnia.

Dr. Singh has a strong interest in mentoring the next generation of researchers. Over the years, she has effectively mentored research of more than 35 students from different education backgrounds. Her mentees have received postdoctoral grant awards from American Heart Association, Sleep Research Society, and The American Physiological Society. Several of her previous students are still pursuing research and clinical training.

Lab: Sleep and Cardio Metabolic Health Lab

Selected Publications

  1. Polonis K, Becari C, Chahal AA, Zhang Y, Allen A, Kellogg TA, Somers VK, Singh P. Chronic intermittent hypoxia triggers a senescence-like phenotype in human white preadipocytes. Scientific Reports, 2020, 10 (1), 1-14. PMID: 32321999 PMCID: PMC7176724

  2. Covassin N, Bukartyk J, Singh P, Calvin AD, St Louis EK, Somers VK. Effects of experimental sleep restriction on ambulatory and sleep blood pressure in healthy young adults – a randomized crossover study. Hypertension, 2021, 78 (3), 859-870 PMID: 34247512 PMCID: PMC8363516

  3. Singh P, Covassin N, Sert-Kuniyoshi FH, Marlatt KL, Romero-Corral A, Davison DE, Singh RJ, Jensen MD, Somers VK. Overfeeding-induced weight gain elicits decreases in sex hormone-binding globulin in healthy males – implications for body fat distribution. Physiological Reports, 2021, 9(23) e15127, DOI: 10.14814/phy2.15127. PMID: 34877821 PMCID: PMC8652402.

  4. Covassin N, Singh P, McCrady-Spitzer SK, St Louis EK, Calvin AD, Levine JA, Somers VK. Effects of experimental sleep restriction on energy intake, energy expenditure, and visceral obesity, Journal of the American College of Cardiology, 2022, 79(13), 1254-1265. PMID: 35361348 PMCID: PMC9187217.

  5. Limberg JK, Baker SE, Peterson-Jones HG, Guo W, Huang A, Jensen MD, Singh P. Endothelin-1 as a novel target for the prevention of metabolic dysfunction with intermittent hypoxia in male participants. American Journal of Physiology, Regulatory, integrative and comparative physiology, 2022, 323(3): R351-R362. PMID: 35816718 PMCID: PMC9423726.

  6. Singh P, Beyl RA, Stephens JM, Noland RC, Richard AJ, Boudreau A, Hebert RC, Ravussin E, Broussard JL, St Onge MP, Marlatt KL. Effect of sleep restriction on insulin sensitivity and energy metabolism in post-menopausal women: A randomized, crossover trial. Obesity, 2023, May 31 (5):1204-1215. 1-12.doi:10.1002/oby.23739. PMID: 36998155, PMCID: PMC10191900.

  7. Zunica ERM, Heintz EC, Dantas WS, Hebert RC, Tanksley M, Beyl RA, Mader EC, Kirwan JP, Axelrod CL, Singh P. Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial. Physiological Reports. 2024, 12(3), e15948. PMID: 38346816. PMCID: PMC10861357

  8. Singh P, Beyl RA, Stephans JM, Richard AJ, Boudreau A, Hebert RC, Noland RC, Burk DH, Ghosh S, Staszkiewicz J, Salbaum JM, Broussard JL, St-Onge M-P, Ravussin E, Marlatt KL. Shortened sleep duration impairs adipose tissue adrenergic stimulation of lipolysis in postmenopausal women. Obesity, 2024, 32(12):2264 -2274. PMID:3946901. PMCID: PMC11598667.

  9. Singh P, Beyl RA, Marlatt KL, Ravussin E. Sleep duration alters overfeeding mediated reduction in insulin sensitivity. JCEM, 2024, doi: 10.1210/clinem/dgae466. PubMed PMID: 39028757.

  10. Peyrel P, Viverito M, Eliser D, Tanksley M, Newton RJ, Carmichael OT, Baron KG, Singh P. Perceptions of sleep and sleep research among African American Adults. Sleep Health, 2025.  11(5):724-730. PMID:40603172

PubMed Bibliography