- 1999 Bachelor of Human Movement Science, Southern Cross University. Lismore, Australia
Major: Exercise Science
- 2000 Bachelor of Human Movement Science with Honours, Southern Cross University. Lismore, Australia
- 2004 Doctor of Philosophy, University of Adelaide. Adelaide, Australia.
- 2011 Master of Science - Clinical Research, Tulane University. New Orleans, LA.
To investigate the impact of the obesogenic environment on health issues in women
- Polycystic ovary syndrome
- Gestational Diabetes
Laboratory Website: https://labs.pbrc.edu/womenshealth
Department: Reproductive Endocrinology and Women's Health
I am a Professor of Clinical Science. My expertise is in human physiology as it relates to the quantification of energy balance, in both controlled and free-living conditions in humans. The epicenter of my work has been in the design and conduct of controlled clinical trials where diet and physical activity are manipulated to modulate body energy stores. Overall our work is conducted with the goal to understand the mechanisms of obesity development as well as to develop and test inventions for effective treatment and prevention. We are also at the forefront of developing and testing e-health technologies such as smartphone apps for delivery of complex lifestyle interventions and enhancing the compliance of individuals to national dietary and exercise guidelines.
As Director of the Reproductive Endocrinology and Women’s Health Laboratory, we are focused on understanding the intergenerational transmission of obesity. I lead extramurally-funded studies in pregnant women (and their infants). I have been PI on three completed NIH funded projects: 3U01DK094418 which was a RCT to test efficacy of a lifestyle intervention program to manage gestational weight gain in overweight and obese pregnant women, R01DK099175, a mechanistic study that characterized the role of energy intake and energy expenditure during pregnancy and postpartum in obese women and R00HD060762 which was a RCT evaluating the role of weight and insulin sensitivity on reproductive function in women with polycystic ovary syndrome. Currently I am PI of two NIH projects - in R01DK124806 we are conducting a highly rigorous proof-of-principle trial to determine the effects of a 6-month gestational intervention with calorie restriction and food provision to promote maternal weight maintenance and fat loss in 100 pregnant women with grades 2 and 3 obesity and in R01NR017644 (the parent grant of this administrative supplement) - we are conducting a community-based RCT to test the efficacy of an e-health intervention for management of gestational weight gain of low income women in the Louisiana WIC program.
A link to my NIH research is here
I have published more than 180 research articles, reviews and book chapters around energy metabolism, insulin sensitivity, obesity, calorie restriction, exercise and pregnancy.
Some of our highlighted work is included here:
- Redman LM, Gilmore LA, Breaux J, Thomas DM, Elkind-Hirsch K, Stewart T, Hsia DS, Burton JH, Apolzan JW, Cain LE, Altazan AD, Ragusa S, Brady H, Davis A, Tilford JM, Sutton EF, Martin CK. Effectiveness of SmartMoms® – a novel e-Health intervention for management of gestational weight gain: A randomized controlled pilot trial. JMIR Mhealth Uhealth. 2017 Sep 13;5(9):e133. PMC5617906
- Most J, Amant MS, Hsia DS, Altazan AD, Thomas DM, Gilmore LA, Vallo PM, Beyl RA, Ravussin E, Redman LM. Evidence-based recommendations for energy intake in pregnant women with obesity. J Clin Invest. 2019 Aug 1;130. PMID: 31369400
- Broskey NT, Klempel MC, Gilmore LA, Sutton EF, Altazan AD, Burton JH, Ravussin E, Redman LM. Assessing energy requirements in women with polycystic ovary syndrome: a comparison against doubly-labeled water. J Clin Endocrinol Metab. 2017 Mar 8. doi: 10.1210/jc.2017-00459 PMID: 28323951
- Gilmore LA, Butte NF, Ravussin E, Han H, Burton JH, Redman LM. Energy Intake and Energy Expenditure For Determining Excess Weight Gain in Pregnant Women. Obstet Gynecol May; 127(5):884-92 (2016). PMID: 27054928
- Most J, Broskey NT, Altazan AD, Beyl RA, St Amant M, Hsia DS, Ravussin E, Redman LM. Is Energy Balance in Pregnancy Involved in the Etiology of Gestational Diabetes in Women with Obesity? Cell Metab. 2019 Feb 5;29(2):231-233. PMID: 30595480
- Redman LM, Smith SR, Burton JH, Martin CK, Il'yasova D, Ravussin E. Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Support the Rate of Living and Oxidative Damage Theories of Aging. Cell Metab. 2018 Apr 3;27(4):805-815.e4. PMID: 29576535
- Most J, Gilmore LA, Smith SR, Han H, Ravussin E, Redman LM. Significant Improvement in Cardiometabolic Health in Healthy Non-Obese Individuals during Caloric Restriction-induced Weight Loss and Weight Loss Maintenance. Am J Physiol Endocrinol Metab. Apr 1;314(4):E396-E405 (2018). PMC5966756
- Marlatt KL, Redman LM, Burton JH, Martin CK, Ravussin E. Persistence of Weight Loss and Acquired Behaviors 2 Years after Stopping a 2-Year Calorie Restriction Intervention. Am J Clin Nutr. Apr;105(4):928-935 (2017). PMC5366052
- Martin CK, Bhapkar M, Pittas A, Pieper CF, Das SK, Williamson DA, Scott T, Redman LM, Stein R, Gilhooly CH, Stewart T, Robinson L, Roberts SB, for the CALERIE Study Group. Effect of calorie restriction on mood, quality of life, sleep, and sexual function in healthy, non-obese adults: Results of the CALERIE 2 randomized controlled trial. JAMA Int Med Jun; 176(6): 743-52 (2016). PMC4905696
A complete list of published work in MyBibliography can be reached here, https://www.ncbi.nlm.nih.gov/sites/myncbi/1ZK6oxdW66o/bibliography/40483137/public/?sort=date&direction=ascending