Education

  • BS, General Studies, Colegio Nacional San Martin, 1962
  • MD/JD, Medicine, Facultad de Medicina-Universidad Nacional del Nordeste, 1970
  • PhD, Pharmacology, Tulane University, 1974
  • Fellowship, Clinical Pharmacology, University of Iowa College of Medicine, 1975
  • Residency, Internal Medicine, University of Connecticut School of Medicine, 1977

Curriculum Vitae

Research Interests

Dr. Lertora’s research has focused on erythropoietin in the anemia of chronic renal disease, cardiovascular pharmacology of beta-adrenergic blocking agents and antiarrhythmic drugs, clinical trials of antiretroviral drugs for HIV/AIDS, pharmacokinetics, drug-drug interactions, and phase I and II clinical trials for drug development.

Selected Publications

  1. Remy KE, Cortés-Puch I, Solomon SB, Sun J, Pockros BM, Feng J, Lertora JJ, Hantgan RR, Liu X, Perlegas A, Warren HS, Gladwin MT, Kim-Shapiro DB, Klein HG, Natanson C. Haptoglobin improves shock, lung injury, and survival in canine pneumonia. JCI Insight. 2018 Sep 20;3(18):e123013. doi: 10.1172/jci.insight.123013. eCollection 2018 Sep 20. PMID: 30232287
  2. Sissung TM, McKeeby JW, Patel J, Lertora JJ, Kumar P, Flegel WA, Adams SD, Eckes EJ, Mickey F, Plona TM, Mellot SD, Baugher RN, Wu X, Soppet DR, Barcus ME, Datta V, Pike KM, DiPatrizio G, Figg WD, Goldspiel BR. Pharmacogenomics Implementation at the National Institutes of Health Clinical Center. J Clin Pharmacol. 2017 Oct;57 Suppl 10(Suppl 10):S67-S77. doi: 10.1002/jcph.993. PMID: 28921647
  3. Bausch DG, Hadi CM, Khan SH, Lertora JJ. Review of the literature and proposed guidelines for the use of oral ribavirin as postexposure prophylaxis for Lassa fever. Clin Infect Dis. 2010 Dec 15;51(12):1435-41. doi: 10.1086/657315. Epub 2010 Nov 8. PMID: 21058912
  4. Watts DH, Park JG, Cohn SE, Yu S, Hitti J, Stek A, Clax PA, Muderspach L, Lertora JJ. Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093. Contraception. 2008 Feb;77(2):84-90. doi:10.1016/j.contraception.2007.10.002. Epub 2007 Dec 21. PMID: 18226670
  5. Mzayek F, Deng H, Mather FJ, Wasilevich EC, Liu H, Hadi CM, Chansolme DH, Murphy HA, Melek BH, Tenaglia AN, Mushatt DM, Dreisbach AW, Lertora JJ, Krogstad DJ. Randomized dose-ranging controlled trial of AQ-13, a candidate antimalarial, and chloroquine in healthy volunteers. PLoS Clin Trials. 2007 Jan 5;2(1):e6. doi:10.1371/journal.pctr.0020006. PMID: 17213921
  6. Lertora JJ, Rege AB, Lacour JT, Ferencz N, George WJ, VanDyke RB, Agrawal KC, Hyslop NE Jr. Pharmacokinetics and long-term tolerance to ribavirin in asymptomatic patients infected with human immunodeficiency virus. Clin Pharmacol Ther. 1991 Oct;50(4):442-9. doi: 10.1038/clpt.1991.162. PMID: 1680594
  7. Lertora JJ, King LW, Donkor KA. The inotropic actions of N-acetylprocainamide: blockade and reversal by propranolol. Angiology. 1986 Dec;37(12 Pt 2):939-49. PMID: 2433968
  8. Lertora JJ, King LW. Cardiovascular actions and pharmacokinetics of desethyl-Nacetylprocainamide in the dog. J Pharmacol Exp Ther. 1986 Sep;238(3):893-9. PMID: 2427689
  9. Lertora JJ, Atkinson AJ Jr, Kushner W, Nevin MJ, Lee WK, Jones C, Schmid FR. Long-term antiarrhythmic therapy with N-acetylprocainamide. Clin Pharmacol Ther. 1979 Mar;25(3):273-82. doi: 10.1002/cpt1979253273. PMID: 310748
  10. Lertora JJ, Mark AL, Johannsen J, Wilson WR, Abboud FM. Selective beta-1 receptor blockade with oral practolol in man. A dose-related phenomenon. J Clin Invest. 1975 Sep;56(3):719-24. doi: 10.1172/JCI108143. PMID: 239966

Pubmed Bibliography