Stephania A. Cormier, Ph.D.

Professor

Department/Laboratory:
Phone:
(225) 763-2691
Fax:
(225) 763-3030
Send E-mail | View CV

EDUCATION

PhD, Louisiana State University A&M Medical Center - New Orleans, Biochemistry & Molecular Biology, 1997

Post Doctoral Fellowship, Mayo Clinic - Scottsdale, Arizona, 1997-2003

RESEARCH INTERESTS

Exposures during early life to environmental factors (i.e., allergens, pollutants, and respiratory viruses) lead to predisposition, development of, or exacerbation of respiratory disease in the adult. We seek: (1) to define the cellular and molecular changes in the pulmonary microenvironment following gestational and/or neonatal exposure; (2) to determine if urban pollutants (e.g., particulates from combustion processes), initiate cellular/molecular events in the developing lung which lead to increased susceptibility to airways disease later in life; (3) to define the impact of respiratory viral infection on pulmonary pathophysiology of the infant; and (4) to understand how urban pollutants impact host defense resulting in enhanced morbidity and increased mortality from respiratory infections. The long-term objective is to realize the initiators of the immune and pathophysiological changes that occur during the early stages of pulmonary airways disease and ultimately to develop effective interventions and therapies.

SELECTED PUBLICATIONS

1. Willis KA, Siefker D, Aziz MM, Gomes CK, Pierre JF, Cormier SA, Talati AJ. The Intestinal Commensal Bacteria Promote Resistance to Lung Injury in Experimental Bronchopulmonary Dysplasia. J Invest Med. 2019;67(2):538-. PMID: WOS:000471859400483

2. Willis KA, Pierre JF, Cormier SA, Talati AJ. Mice without a microbiome are partially protected from lung injury by hyperoxia. Am J Physiol-Lung C. 2019. Epub 2019/10/31. PMID: 31664852

3. Vu LD, Siefker D, Jones TL, You D, Taylor R, DeVincenzo J, Cormier SA. Elevated Levels of Type 2 Respiratory Innate Lymphoid Cells in Human Infants with Severe RSV Bronchiolitis. Am J Respir Crit Care Med. 2019. Epub 2019/06/27. PMID: 31237777

4. Sly PD, Trottier B, Carpenter D, Cha'on U, Cormier S, Galluzzo B, Ghosh S, Goldizen F,
Heacock M, Jagals P, Joshi HD, Kathuria P, Ha LT, Magsumbol MS, Navasumrit P, Prabhakaran P, Sen B, Skelly C, Suraweera I, Vong S, Wangdi C, Suk WA. Children's Environmental Health in South and Southeast Asia: Networking for Better Child Health Outcomes. Annals of global health. 2019;85(1). Epub 2019/03/16. PMID: 30873796

5. Sly PD, Cormier SA, Lomnicki S, Harding JN, Grimwood K. Environmentally Persistent Free Radicals: Linking Air Pollution and Poor Respiratory Health? Am J Respir Crit Care Med. 2019. Epub 2019/06/27. PMID: 31237999.

6. Siefker DT, Vu L, You D, McBride A, Taylor R, Jones TL, DeVincenzo J, Cormier SA. Respiratory Syncytial Virus Disease Severity is Associated with Distinct CD8(+) T Cell Profiles. Am J Respir Crit Care Med. 2019. Epub 2019/10/24. PMID: 31644878.

7. Flanagan TW, Sebastian MN, Battaglia DM, Foster TP, Cormier SA, Nichols CD. 5-HT2 receptor activation alleviates airway inflammation and structural remodeling in a chronic mouse asthma model. Life Sci. 2019;236:116790. Epub 2019/10/19. PMID: 31626791.

8. Sly PD, Cormier SA, Lomnicki S, Harding JN, Grimwood K. Environmentally Persistent Free Radicals: Linking Air Pollution and Poor Respiratory Health? Am J Respir Crit Care Med. 2019. Epub 2019/06/27. PMID: 31237999.

9. Immanuel CN, Teng B, Dong B, Gordon EM, Kennedy JA, Luellen C, Schwingshackl A, Cormier SA, Fitzpatrick EA, Waters CM. Apoptosis signal-regulating kinase-1 promotes inflammasome priming in macrophages. Am J Physiol-Lung C. 2019;316(3):L418-L27. Epub 2019/01/11. PMID: 30628485; PMCID: PMC6459294.

10. Hijano DR, Vu LD, Kauvar LM, Tripp RA, Polack FP, Cormier SA. Role of Type I Interferon (IFN) in the Respiratory Syncytial Virus (RSV) Immune Response and Disease Severity. Front Immunol. 2019;10:566. Epub 2019/04/12. PMID: 30972063; PMCID: PMC6443902.

11. Ghimire A, dela Cruz ALN, Wong R, Navasumrit P, Cormier S, Lomnicki SM. Polybrominated diphenyl ethers (PBDEs) in ambient air samples at the electronic waste (e-waste) reclamation site. Waste Disposal & Sustainable Energy. 2019.
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