Core Services

Administrative Core

Dr. Leanne Redman & Dr. Eric Ravussin

  • Coordination across cores
  • Overall NORC management

Enrichment Program: Dr. Peter Katzmarzyk
Biostatistics: Dr. Kimberly Drews
Pilot and Feasibility Core: Dr. Robery Newton

Human Phenotyping Core

Dr. Corby Martin

Behavior: Dr. Corby Martin

  • Food Intake
  • Physical Activity
  • Behavioral & Psychological Assessment
  • Intervention development and delivery

For more information visit our website.

Energy Balance: Dr. Ursula Whte

  • Imaging
  • Energy Expenditure/Body Composition
  • Carbohydrate Metabolism

For more information visit our website.

Bioinformatics & Molecular Mechanisms Core

Dr. Sujoy Ghosh

Bioinformatics: Dr. Sujoy Ghosh

  • Consultation on all aspects of bioinformatics data analysis
  • Microarray and pre-NGS data analysis
  • Next-generation sequencing data analysis (bulk and single-cell RNA-Seq, ChIP-Seq, ATAC-Seq, metagenomics, spatial transcriptomics)
  • Other omics (proteomics, metabolomics, etc.)
  • Genome-wide association studies (GWAS)
  • Machine learning/AI applications
  • Manuscript and grant writing support

Bioimaging: Dr. David Burk

  • Tissue processing
  • Tissue sectioning
  • Routine and special staining
  • Immunohistochemistry & Immunofluorescence
  • Confocal imaging
  • Epifluorescence imaging
  • Digital slide scanning
  • Tissue clearing
  • 3D Light Sheet Microscopy

For more information visit our website.

Genomics: Dr. J. Michael Salbaum

  • DNA & RNA quality control
  • Quantitative Real-Time PCR
  • Robotic pipetting
  • Sanger DNA sequencing
  • Next-gen sequencing:
  • Bulk RNA Seq
  • Single-Cell RNA Seq
  • Chromatin studies
  • Gut microbiome
  • Bioinformatics

For more information visit our website

Animal Models & Phenotyping Core

Dr. Robert Kesterson

Phenotyping: Dr. Christopher Morrison

  • Body Composition
    • TD-NMR
  • Indirect Calorimetry
    • TSE Systems – Phenomaster
    • Sable Systems – Promethion
  • Food/Water Intake
    • BioDAQ
    • TSE Systems – Phenomaster
    • Sable Systems – Promethion
  • Behavioral Assays
    • Activity Monitoring
    • Learning, Memory and Reward
    • Sensory & Psychomotor Function
    • Affective Behaviors

For more information visit our website, Animal Metabolism and Behavior.

Animal Models: Dr. Bob Kesterson

  • Gene Targeting Consultation & Design
    • Knockout (KO)/Knockin (KI) strategy design
    • Specialized projects
    • Conventional transgene techniques
    • CRISPR mediated techniques
    • AAV strategy design
  • Production of transgenic mice
    • Knockout (KO)
      • Conditional
      • CRISPR mediated
    • Knockin (KI)
      • Reporter knockins (EGFP, Cre recombinase, etc)
      • Specialized projects (Point mutations, codon changes, etc.)
      • CRISPR mediated/ssDNA donor
    • Pronuclear or Cytosol Microinjection of Zygotes
    • Construction of targeting vectors
    • gRNA in vitro testing
    • Embryo Transfer Surgeries: Zygote-Blastocyst stages
  • In Vitro Fertilization (IVF)
    • Fresh or frozen sperm
  • Pathogen Free Rederivation of Mice and Rats
  • Cryopreservation and Recovery of Cryopreserved Embryos and Sperm
  • AAV Vector Construction
  • Genotyping

For more information visit our website, Transgenics Core, or email Kayla Fuselier.