Our Faculty
Christopher Morrison, Ph.D.
Assistant Professor

Department/Laboratory:
Neurosignaling
Phone:
(225) 763-3145
 		 Fax:
(225) 763-0260
Send E-mail 
 
Education:
Ph.D., University of Missouri - Columbia, MO, 2001, Animal Science, Reproductive Physiology and Neuroendocrinology
B.S., Louisiana State University, Baton Rouge, LA, 1997, Animal Science, Science and Technology Focus
Research Interests:

Dr. Morrison has a general research interest in whole animal neuroendocrinology and physiology, especially as applied to the neuronal regulation of feeding behavior, body weight homeostasis, reproduction, growth, and metabolism. Of particular interest are the neuronal circuits and intracellular signaling molecules that mediate the action of circulating nutritional signals within the hypothalamus. Dr. Morrison’s recent work has focused on the necessity of various intracellular signaling pathways in mediating leptin and insulin-dependant changes in food intake and neuropeptide gene expression, as well as the possibility that defects in these signaling pathways may contribute to obesity by impairing hypothalamic leptin and insulin action.


Selected Publications:

CL White, PJ Pistell, MN Purpera, S Gupta, OS Fernandez-Kim, TL Hise, JN Keller, DK Ingram, CD Morrison, and AJ Bruce-Keller. Effects of High Fat Diet on Morris Maze Performance, Oxidative Stress, and Inflammation in Rats: Contributions of Maternal Diet. Neurobiology of Disease, 125(3):603-11, 2009.

CL White, MN Purpera, CD Morrison. Maternal obesity is necessary for the programming effect of a high-fat diet on offspring. Am J Physiol Regul Integr Comp Physiol. R1464-72, 2009.

CL White, A Whittington, MJ Barnes, Z Wang, X Xi, RJ Martin, GA Bray, CD Morrison. HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and independent mechanisms. American Journal of Physiology - Endocrinology & Metabolism 296:E291-9, 2009.

CD Morrison. Leptin resistance and the response to positive energy balance. Physiology & Behavior 94: 660–663, 2008.

HR Berthoud and C Morrison. The brain, appetite, and obesity. Annual Reviews of Psychology 59:55-92, 2008.

CD Morrison, X Xi, CL White, J Ye, RJ Martin. Amino acids inhibit Agrp gene expression via an mTOR-dependent mechanism. Am J Physiol Endocrinol Metab. 293:E165-71, 2007.

CD Morrison, CL White, Z Wang, SY Lee, DS Lawrence, WT Cefalu, ZY Zhang, TW Gettys. Increased hypothalamic PTP1B contributes to leptin resistance with age. Endocrinology 148:433-440, 2007.

For a complete list of publications, visit: http://www.researcherid.com/rid/A-6093-2010
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