Vijay Hegde, Ph.D.

Instructor

Department/Laboratory:
Infection and Obesity
Phone:
(225) 763-2771
 
Fax:
(225) 763-2525
Send E-mail  | View CV 
 

EDUCATION

Ph.D.1997. program in Molecular Biology And Biotechnology. University Of Sheffield, Sheffield, UK.
M.S.1992. Botany with specialization in Plant Physiology. University Of Bombay, Bombay, India.

RESEARCH INTERESTS

SELECTED PUBLICATIONS

Hegde V, Yadavilli S, and Deutsch WA. Knockdown of ribosomal protein S3 protects human cells from genotoxic stress. DNA Repair (Amst) 6(1): 94-99, (2007).

Hegde V, Wang M, Mian IS, Spyres L, and Deutsch WA. The high binding affinity of human ribosomal protein S3 to 7, 8-dihydro-8-oxoguanine is abrogated by a single amino acid change. DNA Repair (Amst) 5(7): 810-815, (2006).

Hegde V, Wang M and Deutsch WA. Human Ribosomal Protein S3 Interacts with DNA Base Excision Repair Proteins hAPE/Ref-1 and hOGG1. Biochemistry 43(44):14211-14217, (2004).

Hegde V, Wang M and Deutsch WA. Characterization of human ribosomal protein S3 binding to 7,8-dihydro-8-oxoguanine and abasic sites by surface plasmon resonance. DNA Repair (Amst) 3(2): 121-126, (2004).

Vicente MG, Nurco DJ, Shetty SJ, Osterloh J, Ventre E, Hegde V, Deutsch WA. Synthesis, dark toxicity and induction of in vitro DNA photodamage by a tetra(4-nido-carboranylphenyl) porphyrin. Journal of Photochemistry and Photobiology B: Biology 68: 123-132, (2002).

Dellinger B, Pryor WA, Cueto R, Squadrito GL, Hegde V, Deutsch WA. The role of free radicals in the toxicity of airborne fine particulate matter. Chemical Research In Toxicology 14 (10): 1371-1377, (2001).

Deutsch WA, Kukreja A, Shane B, Hegde V. Phenobarbital, Oxazepam, and Wyeth 14,643 cause DNA damage as measured by the Comet assay. Mutagenesis 16: 439-442, (2001).

Hegde V, Kelley MR, Xu Y, Mian IS, Deutsch WA. Conversion of the bifunctional 8-oxoguanine/b/d AP DNA repair activities of Drosophila ribosomal protein S3 into the human S3 monofunctional b-elimination catalyst through a single amino acid change. Journal of Biological Chemistry 276 (29):27591-27596, (2001).

Hsieh MM, Hegde V, Kelley MR, Deutsch WA. Activation of APE/Ref-1 redox activity mediated by reactive oxygen species and PKC phosphorylation. Nucleic Acids Research 29: 3116-3122, (2001).

Hegde V, Klein H. Requirement for the SRS2 DNA helicase gene in non-homologous end joining in yeast. Nucleic Acids Research 28: 2779-2783, (2000).

Hegde V, McFarlane RJ, Taylor EM, Price C. The genetics of the repair of 5-Azacytidine mediated DNA damage in fission yeast, Schizosaccharomyces pombe. Molecular and General Genetics 251: 483-492, (1996).
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