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William Hansel, Ph.D.
Professor
Department/Laboratory:
William Hansel Cancer Prevention
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Phone:
(225) 763-3198
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Fax:
(225) 763-3030 |
Send
E-mail
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EDUCATION
Ph.D., Cornell University, New York, NY, 1947, Animal Physiology
M.S., Cornell University, New York, NY, 1949, Animal Physiology
RESEARCH INTERESTS
Dr. Hansel's major research interests are in cancer, reproductive biology and nutrition. He currently leads a group of scientists at the Pennington Center and on the LSU Campus that is developing a new method for treating prostate, breast, testes, and ovarian cancers based on targeting lytic peptides to gonadotropin receptors on the cancer cell membranes.
SELECTED PUBLICATIONS
Leuschner C, Hansel W. Membrane disrupting lytic peptides for cancer treatments. Curr Pharm Des. 2004;10(19):2299-310
Zaleska, M., Waclawik, A., Bodek, G., Zezula-Szpyra, A., Li, X., Janowski, T., Hansel, W.H., Rahman, N.A., and Ziecik, A.J. (2004) Growth repression in diethylstilbestrol/dimethylbenz [a]anthracene-induced rat mammary gland tumor using Hecate-CGb conjugate. Exp. Biol. Med. 229:335-344.
Leuschner, C., Enright, F., Gawronska, B., and Hansel, W. (2003) Membrane disrupting lytic peptide conjugates destroy hormone dependent and independent breast cancer cells in vitro and in vivo. Breast Cancer Research Treat., 78:17-27.
Jaroszewski, J.J., Skarzynski, D.J., Blair, R.M., and Hansel, W. (2003) Influence of nitric oxide on the secretory function of the bovine corpus luteum: dependence on cell composition and cell-to-cell communication. Exp. Biol. Med., 228:741-8.
Bodek, G., Rahman, N. A., Zaleska, M., Soliymani, R., Lankinen, H., Hansel, W., Huhtaniemi, I., and Ziecik, A. J. (2003) A novel approach of targeted ablation of mammary carcinoma cells through luteinizing hormone receptors using Hecate-CGb conjugate. Breast Cancer Res. Treat., 79:1-10.
Skarzynski DJ, Jaroszewski JJ, Bah MM, Deptula KM, Barszczewska B, Gawronska B, Hansel W. Administration of a nitric oxide synthase inhibitor counteracts prostaglandin F2-induced luteolysis in cattle. Biol Reprod. 2003 May;68(5):1674-81. Epub 2002 Nov 27
Hansel W. The potential for improving the growth and development of cultured farm animal oocytes. Anim Reprod Sci. 2003 Dec 15;79(3-4):191-201. Review
Jaroszewski JJ, Skarzynski DJ, Hansel W. Nitric oxide as a local mediator of prostaglandin F2alpha-induced regression in bovine corpus luteum: an in vivo study. Exp Biol Med (Maywood). 2003 Oct;228(9):1057-62
Long R, Steinmetz T, Hommelhoff P, Hansel W, Hansch TW, Reichel J. Magnetic microchip traps and single-atom detection. Philos Transact Ser A Math Phys Eng Sci. 2003 Jul 15;361(1808):1375-89
Leuschner C, Enright FM, Gawronska-Kozak B, Hansel W. Human prostate cancer cells and xenografts are targeted and destroyed through luteinizing hormone releasing hormone receptors. Prostate. 2003 Sep 1;56(4):239-49
Zaleska M, Bodek G, Jana B, Hansel W, Ziecik AJ. Targeted destruction of normal and cancer cells through lutropin/choriogonadotropin receptors using Hecate-betaCG conjugate. Exp Clin Endocrinol Diabetes. 2003 May;111(3):146-53
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