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R Alberto Travagli, Ph.D.
Professor
Department/Laboratory:
Neurobiology and Nutrition II - Travagli
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Phone:
(225) 763-2720
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Fax:
(225) 763-0260 |
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Education:
Ph.D., Georgetown University, Washington, DC, 1993
Ph.D., Ferrara University, Ferrara, Italy, 1985
B.S., Gonzaga Scientific Lyceum, Milan, Italy, 1978
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Research
Interests:
Dr. Travagli's research interests focus on the cellular mechanisms underlying the central control of gastrointestinal functions. A combination of in vitro electrophysiological techniques (whole cell patch clamp in thin slices and in primary neuronal cultures of rat brainstem), in vivo techniques (microinjections and extracellular recordings) and immunocytochemical techniques to study the characteristics of neurones of the dorsal motor nucleus of the vagus (DMV) and the nucleus of the tractus solitarius (NTS), i.e. the motor and sensory vagal nuclei, respectively are currently being utilized in his research. These studies aim to elucidate the cellular mechanisms underlying the control that the central nervous system exerts on the physiological functions of the upper gastrointestinal tract. The main hypothesis is that the DMV and the NTS comprise neuronal subpopulations that are organized such that neurones subserving similar functions can be distinguished based on morphological, electrophysiological and pharmacological properties.
" Please visit my lab by clicking here "
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Selected
Publications:
Browning KN, Kalyuzhny AE, Travagli RA. mu-Opioid receptor trafficking on inhibitory synapses in the rat brainstem. J.Neuroscience. 24:7344-7352; 2004
Martinez-Pena Y Valenzuela I, Rogers RC, Hermann GE, Travagli RA Norepinephrine effects on identified neurons of the rat dorsal motor nucleus of the vagus.Am J Physiol Gastrointest Liver Physiol. 286: G333-9; 2004
Rogers RC, Travagli RA and GE Hermann. Noradrenergic neurones in the rat solitary nucleus participate in the oesophageal-gastric relaxation reflex. Am J Physiol Regul Integr Comp Physiol. 2003 Aug;285(2):R479-89.
Browning KN, Travagli RA. Neuropeptide Y and Peptide YY inhibit excitatory synaptic transmission in the rat dorsal motor nucleus of the vagus. J. Physiology 549(3): 775-785; 2003
Travagli RA, Hermann GE, Browning KN and Rogers RC. Musings on the Wanderer: What’s new in our understanding of vago-vagal reflexes? III. Activity Dependent Plasticity in Vago-Vagal Reflexes Controlling the Stomach. Am.J.Physiol. 284: G180-187; 2003
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