T2 Study

Study Type

Healthy Aging & Alzheimer's Disease

Study Purpose

The T2 research study will test the safety, effectiveness and tolerability of an investigational drug on people diagnosed with mild to moderate Alzheimer’s disease.

About the Study

Scientist believe that Alzheimer’s disease may be caused by high levels of a specific type of molecule in the brain called neurotransmitters.  The T2 study will observe whether modifying a specific neurotransmitter (called glutamate), through the use of an investigational drug, can help slow memory loss and prevent the progression of Alzheimer’s disease.

Study Design

Number of Visits:

  • 3 screening visits
  • 8 study visits (after screening)
  • 4 study phone calls


  • Physical and neurological examination
  • Vital signs
  • Body measurements (height, weight)
  • Blood tests
  • Memory tests
  • Diagnostic tests such as MRI, and ECG
  • Lumbar Puncture (optional)

Study Qualifications

To qualify for this research study, participants should:

  • Be 50 to 85 years old
  • Have a diagnoses of probable Alzheimer’s disease
  • Have a study partner that interacts with you at least 3-4 times per week, participates in all clinic visits, and assists with compliance and study procedures
  • Be on a stable dose of Alzheimer’s disease medication for at least 3 months prior to screening for this study

* You may not qualify for this study based on other eligibility criteria not listed. In depth screening tests will ultimately determine eligibility.

Study Duration

Participation in this study will last approximately 1 year.


Compensation of up to $150 is offered for completion of this study.

Study Contact

If you are interested in volunteering for this research study call 225-763-2973 or e-mail dementia@pbrc.edu.


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