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DYNAMMO Study

Study Type

Diabetes/Prevention

Study Purpose

1 in 4 people in the United States do not know they have type 2 diabetes. Pre-diabetes, a condition that may lead to type 2 diabetes, can develop overtime without any symptoms, making disease treatment and management difficult.

The DYNAMMO research study aims to understand what causes pre-diabetes, with the goal of discovering new options to prevent and treat type 2 diabetes.

About the Study

Once enrolled, participants will be randomly assigned to either an exercise or standard of care program. Both groups require 2 overnight stays in the Pennington Biomedical Inpatient Unit.

Study Design

Number of Visits: 

• 2 screening visits
• 6 study visits, including 4 overnight stays
• 5 days per week for 12 weeks for exercise

Procedures:       

• Medical history
• Height and weight
• Vital signs (pulse and blood pressure)
• EKG
• Questionnaires
• Urine Pregnancy Test (women of child bearing potential)
• Blood draws
• Exercise Tests
• Insulin Sensitivity Test
• Oral Glucose Tolerance Test
• DXA Scan (to measure bone, muscle and body fat)
• Muscle Biopsies
• Resting Metabolic Rate (RMR)

Study Qualifications

To qualify for this research study, participants should: 

• Be between 18 to 45 years old
• Have a Body Mass Index (BMI) between 25 - 40 calculate your BMI
• Be diagnosed with or be at risk for Type 2 Diabetes
  • Are you overweight or obese?
  • Do you have a family history of diabetes?
  • Are you physically inactive?
• Not currently be taking any prescription medication including oral contraceptives
• Not be a smoker
• Not participate in regular exercise

* You may not qualify for this study based on other eligibility criteria not listed. The study coordinator will go over this information in detail.

Study Duration

Participation in this research study will last approximately 18 weeks.

Compensation

Compensation of up to $600 is offered for the completion of this study.

Study Contact

If you are interested in volunteering for this research study, click here to screen online, call 225-763-3000 or email clinicaltrials@pbrc.edu.

If you think you may be eligible, please click the button below to screen online.

GET STARTED

Please do not fill out this questionnaire for anyone other than yourself unless you are their legal guardian.
If you know someone who may be interested please direct them to the site or have them call us directly at 225-763-3000.

CLINICAL TRIALS