Study Type

General Health & Wellbeing

Study Purpose

Weight loss is caused by two main factors: reducing the amount a person eats and increasing the amount of energy a person uses in a day. Scientists refer to that use of energy as ‘energy expenditure’.

The ADORE research study will assess the effectiveness of a study drug, in combination with a calorie restricted diet, to determine if it can help increase our body’s energy expenditure and lead to more weight loss than diet and exercise alone.

About the Study

The study consists of 3 to 5 visits to the Pennington Biomedical outpatient clinic as well as a 24-day period during which participants will be required to stay onsite in the Pennington Biomedical inpatient unit. Eligible participants will receive the study medication or placebo via an injection for 20 days.

Study Design

Number of Visits:
  • 1 screening visit
  • 2 study visits
  • 24 day stay at Pennington Biomedical Inpatient Unit
  • Medical history
  • Height and weight
  • Vital signs (pulse and blood pressure)
  • Physical exam
  • Electrocardiogram (ECG) to determine heart health
  • DXA Scan to measure bone density, muscle, and body fat
  • Pregnancy tests
  • Metabolic Chamber
  • Blood tests
  • Urine tests
  • Questionnaires

Study Qualifications

To qualify for this research study, participants should:

  • Be between the ages of 18 – 45 years old
  • Have a BMI between 28-35
  • Not be pregnant
  • Being willing to live onsite at Pennington Biomedical for 24 consecutive days

Study Duration

Participation in this research study will last approximately 5-8 weeks.


Compensation of up to $4,150 is offered for completion of this study.

Study Contact

If you are interested in volunteering for this research study, click here to screen online, call 225-763-3000 or email

If you think you may be eligible, please click the button below to screen online.


Please do not fill out this questionnaire for anyone other than yourself unless you are their legal guardian.
If you know someone who may be interested please direct them to the site or have them call us directly at 225-763-3000.


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