rrAD Study

Study Type

Cognitive Impairment & Alzheimer's Disease

Study Purpose

The purpose of the rrAD research study is to assess the effects of high blood pressure on brain health. Researchers will evaluate whether exercise, blood pressure medications, or the combination of both could help reduce the risk of developing dementia in people who do not show signs of Alzheimer’s disease.

About the Study

Scientists at Pennington Biomedical are working to better understand the potential links between high blood pressure and the future risk for developing dementia.

The rrAD research study will enroll participants who do not currently have dementia, but who do have hypertension (high blood pressure) to assess if exercise, blood pressure medications or a combination of both treatments could reduce cognitive decline (memory loss) and reduce the future risk of developing dementia.

Study Design

Total number of visits required for participants in this study:

  • 15

These visits include:

  • 2 screening visits
  • 3 introductory visits
  • 3 or more weekly exercise visits (scheduled over a 2 year period)
  • 4 study visits (one every 6 months for a 2 year period)
  • 3 follow-up visits

Study Procedures:

  • Health assessment/vital signs (blood pressure, pulse, etc.)
  • Questionnaires
  • Physical and neurological examinations
  • Test for heart health (ECG)
  • Exercise and physical performance testing
  • Blood tests
  • Imaging (MRI)
  • Ultrasound

Study Qualifications

To qualify, participants in this study should:

  • Be between the ages of 60-85 years old
  • Have concerns about memory loss or have an immediate relative with a diagnosis of dementia
  • Have high blood pressure or be on medication for high blood pressure
  • Have a primary care physician 

Study Duration

Participation in this study will last approximately two years.


Total compensation for the completion of this study is $750.

Study Contact

Interested volunteers may call 225-763-2973 or email dementia@pbrc.edu.


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