Jump Start Study

 

Study Type
Weight Loss
Study Purpose
The purpose of this research study is to look at the safety and effectiveness of combining two study drugs for weight loss.
About the Study

There are two study drugs involved in this study.  One of the study drugs is lorcaserin HCl, which was approved by the FDA as Belviq® in 2012, as an addition to a reduced-calorie diet and exercise, for chronic weight management. This research will also study the effect of lorcaserin HCl when combined with a second study drug, phentermine HCl. Phentermine HCl is a generically available drug that was approved in 1959 by the FDA as a short-term addition in a weight reduction plan based on a reduced-calorie diet, behavior changes and exercise. 

Combining the two study drugs in this study is “investigational”, which means that the combination is being tested and is not approved for use by the FDA.

Study Design

Number of visits:

  • 1 Screening visit
  • 6 Clinic visits
  • 1 Phone call

Study procedures:

  • Height, weight, vitals, BMI
  • Blood draws
  • ECG
  • Dietary meetings
  • Questionnaires
  • Urine sample
  • Pregnancy test

Eligible participants  will be randomized to 1 of 3 groups:

  • Belviq and an active phentermine
  • Belviq and one active and one placebo phentermine
  • Belviq and a double placebo phentermine

The study medication will be taken twice daily for 12 weeks. All study procedures and medications are provided at no cost to the participants.

Study Qualifications
  • Age:18-60 years old
  • Weight:
    • BMI 27- 29.9 with at least one weight-related condition such as hypertension, high cholesterol or sleep apnea calculate your BMI
    • BMI ≥ 30 with or without another weight-related condition calculate your BMI
  • Able to walk and perform moderate exercise
Study Duration
18 weeks
Compensation
Earn up to $350 for participation.
Study Contact
If you are interested in volunteering for the Jump Start study, click here to screen online, call 225-763-3000 or email clinicaltrials@pbrc.edu.

If you think you may be eligible, please click the button below to screen online.



Please do not fill out this questionnaire for anyone other than yourself unless you are their legal guardian.
If you know someone who may be interested please direct them to the site or have them call us directly at 225-763-3000.

CALCULATE YOUR BMI

English Calculation
Enter Your Weight: 
 lbs.
Enter Your Height: 
 ft.  in.
Your BMI: