• Ph.D., Comparative Biomedical Sciences, Louisiana State University School of Veterinary Medicine, 2013
  • M.A., Psychology, University of West Florida, 2008
  • B.A., Psychology, University of West Florida, 2004

Research Interests

Feeding disorders often present with comorbidities of emotional disorders such as anxiety and depression; however, the neurobiology forming this connection is not well understood. The lateral hypothalamus is a brain region which is an established regulator of feeding behavior. We recently identified a subset of neurons in the lateral hypothalamus which potently modulate feeding, stress, and anxiety-related behavior. Current efforts in the lab use advanced viral approaches including chemogenetics, optogenetics, and fiber photometry to dissect the molecular and anatomical substrates which contribute to the role of the lateral hypothalamus in feeding, stress, and emotional behavior.

Selected Publications

  1. François, M., Torres, H., Huesing, C., Zhang, R., Saurage, C., Lee, N., Qualls-Creekmore, E., Yu, S., Morrison, C.D., Burk, D., Berthoud, H.R., Münzberg, H. (2019) Sympathetic innervation of the interscapular brown adipose tissue in mouse. Annals New York Academy of Sciences, June 11.
  2. Hill, C.M., Laeger, T., Dehner, M., Albarado, D.C., Clarke, B., Wanders, D., Burke, S.J., Collier, J., Qualls-Creekmore, E., Solon-Biet, S., Simpson, S.J., Berthoud, H.R., Münzberg, H., & Morrison, C.D. (2019) FGF21 signals protein status to the brain and adaptively regulates food choice and metabolism. Cell Reports, 27(10), pp.2934-2947.
  3. Mumphrey, M.B., Hao, Z., Townsend, R., Qualls-Creekmore, E., Yu, S., Lutz, T.A., Münzberg, H., Morrison, C.D., Berthoud, H.R. (2019) Gastric bypass surgery in lean adolescent mice prevents diet-induced obesity later in life. Scientific Reports, 9(1):7881.
  4. Qualls-Creekmore, E. & Münzberg, H. (2018) Modulation of feeding and associated behaviors by lateral hypothalamic circuits. Endocrinology, 159(11), pp.3631-3642.
  5. Rogers, R.C., McDougal, D.H., Ritter, S., Qualls-Creekmore, E., Hermann, G.E. (2018) Response of catecholaminergic neurons in the mouse hindbrain to glucoprivic stimuli is astrocyte dependent. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 315(1), pp.R153-R164.
  6. Yu, S., Cheng, H., François, M., Qualls-Creekmore, E., Huesing, C., He, Y., Jiang, Y., Gao, H., Xu, Y., Zsombok, A., Derbenev, A.V., Nillni, E.A., Burk, D.H., Morrison, C.D., Berthoud, H.R., Münzberg, H. (2018) Preoptic leptin signaling modulates energy balance independent of body temperature regulation, eLife, 7, e33505.
  7. François, M., Qualls-Creekmore, E., Berthoud, H.R., Münzberg, H., & Yu, S. (2017) Genetics-based manipulation of adipose tissue sympathetic innervation. Physiology and Behavior, S0031-9384(17)30272-X.
  8. Chachlaki, K., Malone, S.A., Qualls-Creekmore, E., Hrabovszky, E., Munzberg, H., Giacobini, P., Ango, F., Prevot, V. (2017). Phenotyping of nNOS neurons in the postnatal and adult female mouse hypothalamus. The Journal of Comparative Neurology, 525(15):3177-3189.
  9. Qualls-Creekmore, E., Yu, S., Francois, M., Huesing, C., Hoang, J., Bruce-Keller, A., Burk, D., Berthoud, H.R., Morrison, C.D., & Münzberg, H. (2017) Galanin-expressing GABA neurons in the lateral hypothalamus modulate food reward and non-compulsive locomotion. The Journal of Neuroscience, 37, 25, 6053-6065.
  10. Qualls-Creekmore, E., Gupta, R., & Yoshimura, M. (2017) Isoform specificity of the effect of alcohol on recombinant adenylyl cyclase. Biochemistry and Biophysics Reports, 10, 157-64.
  11. Münzberg, H., Qualls-Creekmore, E., Berthoud, H.R., Morrison, C.D., Yu, S. (2016) Neural Control of Energy Expenditure. Handbook of Experimental Pharmacology, 233:173-94.
  12. Yu, S., Qualls-Creekmore, E., Rezai-Zadeh, K., Jiang, Y., Berthoud, H.R., Morrison, C.D., Derbenev, A.V., Zsombok, A., Münzberg, H. (2016) Leptin receptor neurons in the preoptic area promote heat-defense responses and hypophagia. The Journal of Neuroscience, 4;36(18):5034- 46.
  13. Münzberg, H., Qualls-Creekmore, E., Yu, S., Morrison, C.D., & Berthoud, H.R. (2016) Hedonics act in unison with the homeostatic system to unconsciously control body weight. Frontiers in Nutrition, 15; 3:6.
  14. Laque, A., Yu, S., Qualls-Creekmore, E., Getty, S., Schwartzenburg, C., Bui, K., Rhodes, C., Berthoud, H.R., Morrison, C., Richards, B., & Münzberg, H. (2015) Leptin regulates nutrient reward via galanin neurons in the lateral hypothalamus. Molecular Metabolism, 4(10), 706-717.
  15. Gupta, R., Qualls-Creekmore, E., & Yoshimura, M. (2013) Real-time monitoring of cAMP during acute ethanol exposure. Alcoholism, Clinical and Experimental Research, 37(9):1456-65.
  16. Dokphrom U., Qualls-Creekmore E., Yoshimura M. (2011) Effects of alcohols on recombinant adenylyl cyclase type 7 expressed in bacteria. Alcoholism, clinical and experimental research, 35(11):1915-22.
  17. Tong, M., Qualls-Creekmore, E., Browning, K.N., Travagli, A.T., & Holmes, G.M. (2010) Experimental spinal cord injury in rats diminishes gastric sensitivity to cholecystokinin-8s. Neurogastroenterology and Motility, 23(2), e69-79.
  18. Qualls-Creekmore, E., Tong, M., & Holmes, G.M. (2010) Time-course of recovery of gastric emptying and motility in rats with experimental spinal cord injury. Neurogastroenterology and Motility, 22(1), 62-69.
  19. Qualls-Creekmore, E., Tong, M., & Holmes, G.M. (2010) Gastric emptying of enterally administered liquid meal in conscious rats and during sustained anesthesia. Neurogastroenterology and Motility, 22(2), 181-185.
  20. Holmes, G.M., Browning, K.N., Tong, M., Qualls-Creekmore, E., & Travagli, R.A. (2009) Vagally-mediated effects of glucagon-like peptide 1 (GLP 1): in vitro and in vivo actions. Journal of Physiology, 587, 4749-4759.