Study Type

General Health & Wellbeing

Study Purpose

More than 30 million people in the United States have type 2 diabetes, and 1 in 4 of them don’t know they have it. The main symptom of type 2 diabetes is high blood sugar levels resulting from the body failing to use insulin properly. This condition, referred to as insulin resistance, may develop overtime without any symptoms, making disease treatment and management difficult.

The DYNAMMO research study aims to understand what causes insulin resistance, with the goal of discovering new options to prevent and treat type 2 diabetes.

About the Study

Once enrolled, participants will be randomly assigned to one of two groups. Both groups will complete the same procedures, but the order of the procedures differ. Both groups require 4 overnight stays in the Pennington Biomedical Inpatient Unit.

Study Design

Number of Visits: 

  • 2 screening visits
  • 6 study visits, including 4 overnight stays


  • Medical history
  • Height and weight
  • Vital signs (pulse and blood pressure)
  • EKG
  • Questionnaires
  • Urine Pregnancy Test (women of child bearing potential)
  • Blood draws
  • Exercise Test
  • Insulin Sensitivity Test
  • Oral Glucose Tolerance Test
  • DXA Scan (to measure bone, muscle and body fat)
  • Muscle Biopsies
  • Resting Metabolic Rate (RMR)

Study Qualifications

To qualify for this research study, participants should: 

  • Be between 18 to 45 years old
  • Have a Body Mass Index (BMI) of 18-25 calculate your BMI
  • Not currently be taking any prescription medication including oral contraceptives

* You may not qualify for this study based on other eligibility criteria not listed. The study coordinator will go over this information in detail.

Study Duration

Participation in this research study will last approximately 6-8 weeks.


Compensation of up to $600 is offered for the completion of this study.

Study Contact

If you are interested in volunteering for this research study, click here to screen online, call 225-763-3000 or emailclinicaltrials@pbrc.edu.

If you think you may be eligible, please click the button below to screen online.


Please do not fill out this questionnaire for anyone other than yourself unless you are their legal guardian.
If you know someone who may be interested please direct them to the site or have them call us directly at 225-763-3000.


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