The HERITAGE Family Study

George Argyropoulos | Claude Bouchard | Jacob Brand | Tuomo Rankinen | Eric E. Snyder
Margarita Teran-Garcia | Ruth Loos | Brandon M. Walts
Anik Boudreau | Jessica Watkins |
Publications
Obesity Gene Map Database | OGMDB Information | OGM2003_paper.pdf
Miscellaneous

HERITAGE --Genetics, Response to Exercise, Risk Factors

 

Publications

1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2009
2010
2011
2012
2013
2014

 

 

1995


1. Bouchard C, Leon AS, Rao DC, Skinner JS, Wilmore JH and Gagnon J.
The HERITAGE Family Study: Aims, design, and measurement protocol.
Medicine and Science in Sports and Exercise 27:721-729, 1995.
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1996

2. Gagnon J, Province MA, Bouchard C, Leon AS, Skinner JS,
Wilmore JH and Rao DC. The HERITAGE Family Study: Quality
assurance and quality control. Annals of Epidemiology 6:520-529, 1996.
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3. Wilmore JH, Stanforth PR, Gagnon J, Leon AS, Rao DC, Skinner JS and
Bouchard C. Endurance exercise training has a minimal effect on resting heart rate: The HERITAGE Study. Medicine and Science in Sports and Exercise 28:829-835, 1996.

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1997

4. Daw EW, Province MA, Gagnon J, Després JP, Bouchard C, Leon AS, Skinner JS, Wilmore JH and Rao DC. Reproducibility of the HERITAGE Family Study intervention protocol: Drift over time. Annals of Epidemiology 7: 452-462, 1997.
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5. El-Moalem HE, Gagnon J, Province M, Bouchard C, Leon AS, Skinner JS, Wilmore JH and Rao DC. Race differences in reproducibilities: The HERITAGE FamilyStudy. American Journal of Human Biology 9:415-424, 1997.

6. Gagnon J, Ho-Kim MA, Chagnon YC, Pérusse L, Dionne FT, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Absence of linkage between VO2max
and its response to training with markers spanning chromosome 22.
Medicine and Science in Sports and Exercise 29: 1448-1453, 1997.
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7. Pérusse L, Collier G, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Nadeau A, Zimmet PZ and Bouchard C. Acute and chronic effects of exercise on leptin levels in humans. Journal of Applied Physiology 83: 5-10, 1997.
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8. Pérusse L, Rice T, Després JP, Bergeron J, Province MA, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Familial resemblance of plasma lipids, lipoproteins and postheparin lipoprotein and hepatic lipases in the HERITAGE Family Study. Arteriosclerosis, Thrombosis and Vascular Biology 17: 3263-3269, 1997.
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9. Rice T, Després JP, Daw EW, Gagnon J, Borecki IB, Pérusse L, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Familial resemblance for abdominal visceral fat: The HERITAGE Family Study. International Journal of Obesity 21: 1024-1031, 1997.
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10. Rice T, Daw EW, Gagnon J, Bouchard C, Leon AS, Skinner JS, Wilmore JH and Rao C. Familial resemblance for body composition measures: The HERITAGE Family Study. Obesity Research 5: 557-562, 1997.
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11. Rice T, Després JP, Pérusse L, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Segregation analysis of abdominal visceral fat: The HERITAGE Family Study. Obesity Research 5: 417-424, 1997. view article

12. Rivera MA, Dionne FT, Simoneau JA, Pérusse L, Chagnon M, Chagnon Y, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Muscle-specific creatine kinase gene polymorphism and VO2max in the HERITAGE Family Study. Medicine and Science in Sports and Exercise 29: 1311-1317, 1997.
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13. Wilmore JH, Leon AS, Rao DC, Skinner JS, Gagnon J and Bouchard C. Genetics, response to exercise, and risk factors: The HERITAGE Family Study. In: Simopoulos AP (ed): Nutrition and Fitness: Evolutionary Aspects, Children's Health, Programs and Policies. World Rev Nutr Diet. Basel, Karger, 1997, vol 81, pp 72-83. (Proceedings of the Third International Conference on Nutrition and Fitness, Athens, Greece).
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14. Wilmore JH, Stanforth PR, Domenick MA, Gagnon J, Daw EW, Leon AS, Rao DC, Skinner JS and Bouchard C. Reproducibility of anthropometric and body composition measurements: The HERITAGE Family Study. International Journal of Obesity 21: 297-303, 1997.
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15. Bouchard C, Daw EW, Rice T, Pérusse L, Gagnon J, Province MA, Leon AS, Rao DC, Skinner JS and Wilmore JH. Familial resemblance for VO2max in the sedentary state: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 30: 252-258, 1998.
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1998

16. Wilmore JH, Stanforth PR, Turley KR, Gagnon J, Daw EW, Leon AS, Rao DC, Skinner JS and Bouchard C. Reproducibility of cardiovascular, respiratory and metabolic responses to submaximal exercise: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 30: 259-265, 1998.
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17. Gu C, Borecki IB, Gagnon J, Bouchard C, Leon AS, Skinner JS, Wilmore JH and Rao DC. Familial resemblance for resting blood pressure with particular reference to racial differences: Preliminary analyses from the HERITAGE Family Study. Human Biology 70: 77-90, 1998.
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18. Rivera MA, Wolfarth B, Dionne FT, Chagnon M, Simoneau JA, Boulay MR, Song TMK, Pérusse L, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Keul J and Bouchard C. Three mitochondrial DNA restriction polymorphisms in elite endurance athletes and sedentary controls. Medicine and Science in Sports and Exercise 30: 687-690, 1998. view article

19. Wilmore JH, Stanforth PR, Hudspeth LA, Gagnon J, Daw EW, Leon AS, Rao DC, Skinner JS and Bouchard C. Alterations in resting metabolic rate as a consequence of 20 wk of endurance training: the HERITAGE Family Study. American Journal of Clinical Nutrition 68: 66-71, 1998.
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20. Hong Y, Rice T, Gagnon J, Després JP, Nadeau A, Pérusse L, Bouchard C, Leon AS, Skinner JS, Wilmore JH and Rao DC. Familial clustering of insulin and abdominal visceral fat: The HERITAGE Family Study. Journal of Clinical Endocrinology and Metabolism 83: 4239-4245, 1998.
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1999

21. Stanforth PR, Ruthven MD, Gagnon J, Bouchard C, Leon AS, Rao DC, Skinner JS and Wilmore JH. Accuracy of prediction equations to estimate submaximal VO2 during cycle ergometry: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 31: 183-188, 1999.
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22. An P, Rice T, Gagnon J, Borecki IB, Pérusse L, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Familial aggregation of resting blood pressure and heart rate in a sedentary population: The HERITAGE Family Study.
American Journal of Hypertension 12: 264-270, 1999.
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23. Després JP, Gagnon J, Bergeron J, Couillard C, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Plasma post-heparin lipase activities in the HERITAGE Family Study. The reproducibility, gender differences and associations with lipoprotein levels. Clinical Biochemistry 32: 157-165, 1999.
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24. Rivera MA, Pérusse L, Simoneau JA, Gagnon J, Dionne FT, Leon AS, Skinner JS, Wilmore JH, Province M, Rao DC and Bouchard C. Linkage between a muscle-specific CK gene marker and VO2max in the HERITAGE Family Study. Medicine and Science
in Sports and Exercise 31: 698-701, 1999.
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25. Hong Y, Rice T, Després JP, Gagnon J, Nadeau A, Bergeron J, Pérusse L, Bouchard C, Leon AS, Skinner JS, Wilmore JH and Rao DC. Evidence of a major locus for lipoprotein lipase (LPL) activity in addition to a pleiotropic locus for both LPL and fasting insulin: results from the HERITAGE Family Study.
Atherosclerosis 144: 393-401, 1999.
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26. Rivera MA, Pérusse L, Gagnon J, Dionne FT, Leon AS, Rao DC, Skinner JS,Wilmore JH, Sjöström L and Bouchard C. A mitochondrial DNA D-loop polymorphism and obesity in three cohorts of women. International Journal of Obesity 23:666-668, 1999.
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27. Wilmore JH, Després JP, Stanforth PR, Mandel S, Rice T, Gagnon J, Leon AS, Rao DC, Skinner JS and Bouchard C. Alterations in body weight and composition consequent to 20 wk of endurance training: the HERITAGE Family Study. American Journal of Clinical Nutrition 70:346-352, 1999.
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28. Rankinen T, Gagnon J, Pérusse L, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Body fat, resting and exercise blood pressure and the angiotensinogen M235T polymorphism: The HERITAGE Family Study.
Obesity Research 7:423-430, 1999.
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29. Sun G, Gagnon J, Chagnon YC, Pérusse L, Després JP, Leon AS, Wilmore JH, Skinner JS, Borecki I, Rao DC and Bouchard C. Association and linkage between an insulin-like growth factor-1 gene polymorphism and fat free mass in the HERITAGE Family Study. International Journal of Obesity 23:929-935, 1999.
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30. Bouchard C, An P, Rice T, Skinner JS, Wilmore JH, Gagnon J, Pérusse L, Leon A and Rao DC. Familial aggregation of VO2max response to exercise training: Results from the HERITAGE Family Study. Journal of Applied Physiology 87(3):1003-1008, 1999.
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31. Rice T, Hong Y, Pérusse L, Després JP, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Total body fat and abdominal visceral fat response to exercise training in the HERITAGE Family Study: Evidence for major locus but no multifactorial effects. Metabolism 48(10):1278-1286, 1999.
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32. Skinner JS, Wilmore KM, Jaskólska A, Jaskólski A, Daw EW, Rice T, Gagnon J, Leon AS, Wilmore JH, Rao DC and Bouchard C. Reproducibility of maximal exercise test data in the HERITAGE Family Study. Medicine and Science in Sports and Exercise 31(11):1623- 1628, 1999.
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2000



33. An P, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Cross-trait familial resemblance for resting blood pressure and body composition and fat distribution: The HERITAGE Family Study.
American Journal of Human Biology 12(1): 32-41, 2000.
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34. Rankinen T, Pérusse L, Borecki IB, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. The Na,K-ATPase a2 gene
and trainability of cardiorespiratory endurance: The HERITAGE Family Study. Journal of Applied Physiology 88(1): 346-351, 2000.
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35. Bouchard C, Rankinen T, Chagnon YC, Rice T, Pérusse L, Gagnon J, Borecki IB, An P, Leon AS, Skinner JS, Wilmore JH, Province M and Rao DC. Genomic scan for maximal oxygen uptake and its response to training in the HERITAGE Family Study. Journal of Applied Physiology 88(2): 551-559, 2000.
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36. Chagnon YC, Wilmore JH, Borecki IB, Gagnon J, Pérusse L, Chagnon M, Collier GR,Leon AS, Skinner JS, Rao DC and Bouchard C. Associations between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE Family Study. Journal of Clinical Endocrinology and Metabolism 88(1): 29-34, 2000.
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37. Skinner JS, Jaskólski A, Jaskólska A, Wilmore K, Krasnoff J, Gagnon J, Province MA,Leon AS, Rao DC, Wilmore JH and Bouchard C. Adaptation to a standardized training program and changes in fitness in a large, heterogeneous population: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 32(1): 157-161, 2000.
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38. An P, Rice T, Gagnon J, Borecki IB, Bergeron J, Després JP, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Segregation analysis of apolipoproteins A-1 and B-100 measured before and after an exercise training program: The HERITAGE Family Study. Arteriosclerosis, Thrombosis and Vascular Biology 20(3): 807-814, 2000.
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39. Rankinen T, Pérusse L, Gagnon J, Chagnon YC, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Angiotensin-converting enzyme ID polymorphism and fitness phenotypes in the HERITAGE Family Study. Journal of Applied Physiology 88(3): 1029-1035, 2000.
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40. Couillard C, Gagnon J, Bergeron J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Després JP, and Bouchard C. Contribution of body fatness and adipose tissue distribution to the age variation in plasma steroid hormone concentrations in men:The HERITAGE Family Study.Journal of Clinical Endocrinology and Metabolism 85(3): 1026-1031, 2000.
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41. An P, Rice T, Gagnon J, Hong Y, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. A genetic study of dehydroepiandrosterone sulfate measured before and after a 20-week endurance exercise training program: The HERITAGE Family Study. Metabolism 49(3): 298-304, 2000.
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42. Hong Y, Després JP, Rice T, Nadeau A, Province MA, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Evidence of pleiotropic loci for fasting insulin, total fat mass, and abdominal visceral fat in a sedentary population: The HERITAGE Family Study. Obesity Research 8(2): 151-159, 2000.
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43. Pérusse L, Rice T, Province MA, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Familial aggregation of amount and distribution of subcutaneous fat and their responses to exercise training in the HERITAGE Family Study. Obesity Research 8(2): 140-150, 2000.
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44. Garenc C, Pérusse L, Gagnon J, Chagnon YC, Bergeron J, Després JP, Province MA, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Linkage and association studies of the lipoprotein lipase gene with post-heparin plasma lipase activities, body fat and plasma lipid and lipoprotein concentrations: The HERITAGE Family Study. Metabolism 49(4): 432-439, 2000.
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45. Leon AS, Rice T, Mandel S, Després JP, Bergeron J, Gagnon J, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Blood lipid response to 20 weeks of supervised exercise in a large biracial population: The HERITAGE Family Study. Metabolism 49 (4): 513-520, 2000.
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46. An P, Rice T, Pérusse L, Borecki IB, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Complex segregation analysis of blood pressure and heart rate measured before and after a 20-week endurance exercise training program: The HERITAGE Family Study. American Journal of Hypertension 13: 488-497, 2000.
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47. Katzmarzyk P, Pérusse L, Rice T, Gagnon J, Skinner JS, Wilmore JH, Leon AS, Rao DC and Bouchard C. Familial resemblance in coronary heart disease risk: The HERITAGE Family Study. Ethnicity and Disease 10: 138-47, 2000.
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48. Rankinen T, Gagnon J, Pérusse L, Chagnon YC, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. AGT M235T and ACE ID polymorphisms and exercise blood pressure in the HERITAGE Family Study. American Journal of Physiology Heart and Circulatory Physiology 279:H368-H374, 2000.
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49. Hong Y, Rice T, Gagnon J, Pérusse L, Province M, Bouchard C, Leon AS, Skinner JS, Wilmore JH, Rao DC and Després JP. Familiality of triglyceride and LPL response to exercise training: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 32: 1438-1444, 2000.
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50. Després JP, Couillard C, Gagnon J, Bergeron J, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Race, visceral adipose tissue, plasma lipids, and lipoprotein lipase activity in men and women. The Health, Risk Factors, Exercise Training, and
Genetics (HERITAGE) Family Study. Arteriosclerosis, Thrombosis and Vascular Biology 20; 1932-38, 2000.
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51. An P, Rice T, Borecki IB, Pérusse L, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Major gene effect on subcutaneous fat distribution in a sedentary population and its response to exercise training: The HERITAGE Family Study. American Journal of Human Biology 12; 600-609, 2000.
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52. Stanforth PR, Gagnon J, Rice T, Bouchard C, Leon AS, Rao DC, Skinner JS and Wilmore JH. Reproducibility of resting blood pressure and heart rate measurements: The HERITAGE Family Study. Annals of Epidemiology 10; 271-277, 2000.
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53. An P, Rice T, Gagnon J, Hong Y, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. A genetic study of sex hormone binding globulin measured before and after a 20-week endurance exercise training program: The HERITAGE Family Study. Metabolism 49; 1014-1020, 2000
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54. Rankinen T, Rice T, Pérusse L, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. NOS3 Glu298Asp genotype and blood pressure response to endurance training: The HERITAGE Family Study. Hypertension 36:885-889, 2000
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55. Wilmore JH, Stanforth PR, Gagnon J, Rice T, Mandel S, Leon AS, Rao DC, Skinner JS, Bouchard C. Cardiac output and stroke volume changes with endurance training: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:99-106, 2001
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56. Wilmore JH, Stanforth PR, Gagnon J, Rice T, Mandel S, Leon AS, Rao DC, Skinner JS and Bouchard C. Heart rate and blood pressure changes with endurance training: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:107-116, 2001.
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57. An P, Rice T, Gagnon J, Leon AS, Skinner JS, Bouchard C, Rao DC and Wilmore JH. Familial aggregation of stroke volume and cardiac output during submaximal exercise: The HERITAGE Family Study. International Journal of Sports Medicine 21: 566-572, 2000.
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2001

58. Rivera M, Echegaray M, Rankinen T, Pérusse L, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Angiogenin gene-race interaction for resting and exercise BP phenotypes: The HERITAGE Family Study. Journal of Applied Physiology 90: 1232-1238, 2001.
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59. Skinner JS, Jaskólski A, Jaskólska A, Krasnoff J, Gagnon J, Leon AS, Rao DC, Wilmore JH and Bouchard C. Age, sex, race, initial fitness and response to training: The HERITAGE Family Study. Journal of Applied Physiology 90:1770-1776, 2001.
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60. Chagnon YC, Rice T, Pérusse L, Borecki IB, Ho-Kim MA, Lacaille M, Pare C, Bouchard L, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Genome scan for genes affecting body composition before and after training in Caucasians from HERITAGE. Journal of Applied Physiology 90:1777-1787, 2001.
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61. Katzmarzyk PT, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Fitness, fatness and estimated coronary heart disease risk: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:585-590, 2001.
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62. Pérusse L, Gagnon J, Province MA, Rao DC, Wilmore JH, Leon AS, Bouchard C and Skinner JS. Familial aggregation of submaximal aerobic performance in the HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:597-604, 2001
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63. Garenc C, Pérusse L, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. The TRP64arg polymorphism in the b3-adrenergic receptor gene is not associated with training-induced changes in body composition: The HERITAGE Family Study. Obesity Research 9: 337-341, 2001.
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64. Ukkola O, Gagnon J, Rankinen T, Thompson PA, Hong Y, Pérusse L, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C, Age, body mass index, race and other determinants of steroid hormone variability: The HERITAGE Family Study. European Journal of Endocrinology 145: 1-9, 2001.
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65. Katzmarzyk P, Leon AS, Rankinen T, Gagnon J, Skinner JS, Wilmore JH, Rao DC, Bouchard C. Changes in blood lipids consequent to endurance training related to changes in body fatness and aerobic fitness. Metabolism 50: 841-848, 2001.
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66. Couillard C, Després JP, Lamarche B, Bergeron J, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Effect of endurance exercise training on plasma HDL cholesterol levels depend on the levels of triglycerides. Evidence from men of the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Arteriosclerosis, Thrombosis and Vascular Biology 21: 1226 - 1232, 2001.
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67. Rankinen T, An P, Sun G, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Genomic scan for exercise blood pressure in the HERITAGE Family Study. Hypertension38: 30-37, 2001.
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68. An P, Rice T, Gagnon J, Hong Y, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Race differences in the pattern of familial aggregation for dehydroepiandrosterone sulfate and its responsiveness to training in the HERITAGE Family Study. Metabolism 50; 916-920, 2001.
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69. Hong Y, Gagnon J, Rice T, Pérusse L, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Familial resemblance for free androgens and androgen glucuronides in sedentary Black and White individuals: The HERITAGE Family Study. Journal of Endocrinology 170; 485-492, 2001
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70. Garenc C, Pérusse L, Bergeron J, Chagnon YC, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Evidence of LPL gene-exercise interaction for body fat and LPL activity: the HERITAGE Family Study. Journal of Applied Physiology 91:1334-40, 2001.
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71. Hong Y, Weisnagel SJ, Rice T, Sun G, Mandel SA, Gu C, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bergman RN, Bouchard C and Rao DC. Familial resemblance for glucose and insulin metabolism indices derived from an intravenous glucose tolerance test in Blacks and Whites of the HERITAGE Family Study. Clinical Genetics 60:22-30, 2001.
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72. Rivera MA, Echegaray M, Rankinen T, Pérusse L, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. TGF-B1 gene-race interactions for resting and exercise blood pressure in the HERITAGE Family Study. Journal of Applied Physiology 91:1808-1813, 2001.
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73.
Gaskill S, Rice T, Bouchard C, Gagnon J, Rao DC, Skinner J, Wilmore J and Leon AS. Familial resemblance in ventilatory threshold: the HERITAGE Family Study. Medicine and Science in Sports and Exercise 33:1832-1840, 2001.
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74. An P, Rice T, Gagnon J, Borecki IB, Rankinen T, Gu C, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Population differences in the pattern of familial aggregation for sex hormone binding globulin and its response to exercise training: The HERITAGE Family Study. Am J Hum Biol 13:832-837, 2001.

75. An P, Rosmond R, Borecki IB, Ukkola O, Rice T, Gagnon J, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Genome-wide linkage scan to detect loci influencing levels of dehydroepiandrosterones in the HERITAGE Family Study. Metabolism 50: 1315-1322, 2001.
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76. Wilmore JH, Green JS, Stanforth PR, Gagnon J, Rankinen T, Leon AS, Rao DC, Skinner JS, Bouchard C. Relationship of changes in maximal and submaximal aerobic fitness to changes in cardiovascular disease and non-insulin-dependent diabetes risk factors with endurance training: The HERITAGE Family Study. Metabolism 50: 1255-63, 2001
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77. Gaskill SE, Walker AJ, Serfass RA, Bouchard C, Gagnon J, Rao DC, Skinner JS, Wilmore JH and Leon AS. Changes in ventilatory threshold with exercise training in a sedentary population: The HERITAGE Family Study. International Journal of Sports Medicine 22: 586-592, 2001.
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78. Bergeron J, Couillard C, Després JP, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Race differences in the response of postheparin plasma lipoprotein lipase and hepatic lipase activities to endurance exercise training in men. Results from the HERITAGE Family Study. Atherosclerosis 159:399-406, 2001
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79. Leon AS, Gaskill SE, Rice T, Bergeron J, Gagnon J, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Variability in the response of HDL cholesterol to exercise training in the HERITAGE Family Study. International Journal of Sports Medicine 23:1-9, 2002.
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2002

80. Green JS, Stanforth PR, Gagnon J, Leon AS, Rao DC, Skinner JS, Bouchard C, Rankinen T and Wilmore JH. Menopause, estrogen, and training effects on exercise hemodynamics: The HERITAGE Family Study. Medicine and Science in Sports and Exercise 34:74-82, 2002.
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81. Lanouette C-M, Chagnon YC, Rice T, Perusse L, Muzzin P, Giacobino JP, Gagnon J, Wilmore JH, Leon AS, Skinner JS, Rao DC and Bouchard C. Uncoupling protein 3 gene is associated with body composition changes with training in HERITAGE study. Journal of Applied Physiology 92:1111-1118, 2002.
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82. Tanaka S, Togashi K, Rankinen T, Perusse L, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Is adiposity at normal body weight relevant for cardiovascular disease risk? International Journal of Obesity 26:176-183, 2002
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83. Garenc C, Pérusse L, Chagnon YC, Rankinen T, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. The hormone-sensitive lipase gene and body composition: The HERITAGE Family Study. International Journal of Obesity 26:220-227, 2002.
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84. Rice T, Chagnon YC, Pérusse L, Borecki IB, Ukkola O, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. A genome-wide linkage scan for abdominal subcutaneous and visceral fat in black and white families: the HERITAGE Family Study. Diabetes 51:848-855, 2002
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85. Rankinen T, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. G protein b3 polymorphism and hemodynamic and body composition phenotypes in the HERITAGE Family Study. Physiological Genomics 8:151-157, 2002
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86. Feitosa M, Rice T, Rosmond R, Borecki IB, An P, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. A genetic study of cortisol measured before and after endurance training: The HERITAGE Family Study. Metabolism 51: 360-365, 2002
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87. Rice T, Despres JP, Perusse L, Hong Y, Province MA, Bergeron J, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Familial aggregation of blood lipid response to exercise training in the health, risk factors, exercise training and genetics (HERITAGE) Family Study. Circulation 105:1904-1908, 2002.
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88. Rice T, Chagnon YC, Borecki IB, Pérusse L, Collier G, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Familial resemblance for plasma leptin: sample homogeneity across adiposity and ethnic groups. Obesity Research 10:351-360, 2002
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89. Jackson AS, Stanforth PR, Gagnon J, Rankinen T, Leon AS, Rao DC, Skinner JS, Bouchard C, Wilmore JH. The effect of sex, age, and race on estimating percent body fat from body mass index: The HERITAGE Family Study. International Journal of Obesity 26:789-796, 2002
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90. Rice T, An P, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Heritability of HR and BP response to endurance exercise training in the HERITAGE Family Study. Medicine and Science in Sports and Exercise 34;972-979, 2002.
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91. Rice T, Rankinen T, Chagnon YC, Province MA, Pérusse L, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Genomewide linkage scan for resting blood pressure: the HERITAGE Family Study. Hypertension 39:1037-1043, 2002
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92. Garenc C, Perusse L, Chagnon YC, Rankinen T, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. The alpha2 –adrenergic receptor gene and body fat content and distribution: The HERITAGE Family Study. Molecular Medicine 8: 88-94, 2002
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93. Ukkola O, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JF, Rao DC, Bouchard C. A genome-wide linkage scan for steroids and SHBG levels in Black and White families: The HERITAGE Family Study. Journal of Clinical Endocrinology and Metabolism 87: 3708-3720, 2002
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94. Rankinen T, An P, Pérusse L, Rice T, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Genome-wide linkage scan for exercise stroke volume and cardiac output in the HERITAGE Family Study. Physiological Genomics 10; 57-62, 2002.
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95. Ukkola O, Ravussin E, Jacobson P, Pérusse L, Rankinen T, Tschöp M, Heiman ML, Leon AS, Rao DC, Skinner JS, Wilmore JH, Sjöstrom L and Bouchard C. Role of ghrelin polymorphisms in obesity based on three different studies. Obesity Research 10; 782-791, 2002
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96. Feitosa MF, Gaskill SE, Rice T, Rankinen T, Bouchard C, Rao DC, Wilmore JH, Skinner JS, Leon AS. Major gene effects on exercise ventilatory threshold: the HERITAGE Family Study. Journal of Applied Physiology 93;1000-1006, 2002
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97. Argyropoulos G, Rankinen T, Neufeld DR, Rice T, Province MA, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. A polymorphism in the human agouti-related protein is associated with late-onset obesity. Journal of Clinical Endocrinology and Metabolism 87;4198-4202, 2002
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98. Jacobson P, Ukkola O, Rankinen T, Snyder EE, Leon AS, Rao DC, Skinner JS, Wilmore JH, Lonn L, Cowan Jr GS, Sjostrom L, Bouchard C. Melanocortin 4 receptor sequence variations are seldom a cause of human obesity: The Swedish Obese Subjects, the HERITAGE Family Study and a Memphis Cohort. Journal of Clinical Endocrinology and Metabolism 87:4442-4446, 2002
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99. Feitosa MF, Rice T, Rosmond R, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Pleiotropic relationships between cortisol levels and adiposity: The HERITAGE Family Study. Obesity Research 10:1222-1231, 2002
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2003

100. Feitosa MF, Borecki I, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Lack of pleiotropic effects between adiposity and sex hormone-binding globulin levels before and after 20 weeks of exercise training: the HERITAGE Family Study. Metabolism 52:35-41, 2003.
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101. An P, Perusse L, Rankinen T, Borecki IB, Gagnon J, Leon AS, Skinner JH, Wilmore JH, Bouchard C and Rao DC. Familial aggregation of exercise heart rate and blood pressure in response to 20 weeks of endurance training: The HERITAGE Family Study. International Journal of Sports Medicine 24:57-62, 2003
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102. Argyropoulos G, Rankinen T, Bai F, Rice T, Province MA, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. The Agouti Related Protein and Body Fatness in Humans. International Journal of Obesity 27:276-280, 2003
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103. An P, Hong Y, Weisnagel JS, Rice T, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Chagnon YC, Bergman RN, Bouchard C and Rao DC. Genomic scan of glucose and insulin metabolism phenotypes: The HERITAGE Family Study. Metabolism 52:246-53, 2003.
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104. Ukkola O, Rankinen T, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Interactions among the b2- and b3-adrenergic receptor genes and total body fat and abdominal fat level in the HERITAGE Family Study. International Journal of Obesity 27:389-393, 2003.
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105. Garenc C, Pérusse L, Chagnon YC, Rankinen T, Gagnon J, Borecki IB, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Effects of beta-2-adrenergic receptor gene variants on adiposity: The HERITAGE Family Study. Obesity Research 11:612-618, 2003.
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106. Lakka TA, Rankinen T, Weisnagel SJ, Chagnon YC, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. A Quantitative Trait Locus on 7q31 for the Changes in Plasma Insulin in Response to Exercise Training: the HERITAGE Family Study. Diabetes 52:1583-1587, 2003.
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107. Simonen RL, Rankinen T, Perusse L, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. A dopamine D2 receptor gene polymorphism and physical activity in two family studies. Physiology and Behavior 78:751-757, 2003.
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108. Rico-Sanz J, Rankinen T, Joanisse D, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Associations between cardiorespiratory responses to exercise and the C34T AMPD1 gene polymorphism in the HERITAGE Family Study. Physiological Genomics 14:161-166, 2003.
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109. Rankinen T, Rice T, Boudreau A, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Titin is a candidate gene for stroke volume response to endurance training: the HERITAGE Family Study. Physiological Genomics 15;27-33, 2003.
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110. Rico-Sanz J, Rankinen T, Joanisse D, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Familial resemblance of muscle phenotypes in the sedentary state and their responses to training: the HERITAGE Family Study. Medicine and Science in Sports and Exercise 35:1360-1366, 2003.
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111. An P, Borecki IB, Rankinen T, Perusse L, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Evidence of major gene for exercise heart rate and blood pressure at baseline and in response to 20 weeks of endurance training: The HERITAGE Family Study. International Journal of Sports Medicine 24;492-498, 2003.
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112. Katzmarzyk PT, Leon AS, Wilmore JH, Skinner JS, Rao DC, Rankinen T and Bouchard C. Targeting the metabolic syndrome with exercise: Evidence from the HERITAGE Family Study. Medicine and Science in Sports and Exercise 35;1703-1709, 2003
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113. Skinner JS, Gaskill SE, Rankinen T, Leon AS, Rao DC, Wilmore JH and Bouchard C. Heart rate vs. VO2 max: Age, Sex, Race, Initial Fitness and Training Response- HERITAGE. Medicine and Science in Sports and Exercise 35:1908-1913, 2003.
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114. Couillard C, Bergeron J, Després JP, Gagnon J, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Apolipoprotein AI and AI:AII containing lipoproteins in white men and women of the HERITAGE Family Study: Associations with metabolic risk profile variables. Metabolism 52:1530-1536, 2003
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115. Desmeules A, Couillard C, Tchernof A, Bergeron J, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Després J-P and Bouchard C. Post-heparin lipolytic enzyme activities, sex hormones and sex hormone-binding globulin (SHBG) in men and women: the HERITAGE Family Study. Atherosclerosis 171:343-350, 2003
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116. Loos R, Katzmarzyk P, Rao DC, Rice T, Leon AS, Wilmore JH, Skinner JS, Rankinen T, Bouchard C. Genome-wide linkage scan for metabolic syndrome in the HERITAGE Family Study. Journal of Clinical Endocrinology and Metabolism 88:5935-5943, 2003
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2004

117. Leon AS, Togashi K, Rankinen T, Despres JP, Rao DC, Skinner J, Wilmore J and Bouchard C. Association of apolipoprotein E polymorphism with blood lipids and maximal oxygen uptake in the sedentary state and after exercise training in the HERITAGE Family Study. Metabolism 53:108-116, 2004
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118. Rico-Sanz J, Rankinen T, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Quantitative trait loci for maximal exercise capacity phenotypes and their responses to training in the HERITAGE Family Study. Physiological Genomics 16;256-260, 2004
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119. Tanaka S, Togashi K, Rankinen T, Perusse L, Leon AS, Rao DC, Skinner JS, Wilmore JH, Despres JP, Bouchard C. Sex differences in the relationships of abdominal fat to cardiovascular disease risk among normal-weight white subjects. International Journal of Obesity 28;320-323, 2004
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120. Janssen I, Katzmarzyk PT, Ross R, Leon AS, Skinner JS, Rao DC, Wilmore JH, Rankinen T and Bouchard C. Fitness alters the association of BMI and waist curcumference with total and abdominal fat. Obesity Research 12;525-537, 2004.
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121. Collaku A, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Wilmore JH and Bouchard C. Genome-wide linkage scan for dietary energy and energy nutrient intakes: The Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) Family Study. American Journal of Clinical Nutrition 79:881-886, 2004.
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122. Sklan EH, Lowenthal A, Korner M, Ritov Y, Landers DM, Rankinen T, Bouchard C, Leon AS, Rice T, Rao DC, Wilmore JH, Skinner JS and Soreq H. Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics Study. Proc Natl Acad Sci 101:5512-5517, 2004.
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123. Lakka TA, Rankinen T, Weisnagel SJ, Chagnon YC, Lakka HM, Ukkola O, Boule N, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Bouchard C. Leptin and leptin receptor gene polymorphisms and changes in glucose homeostasis in response to regular exercise in nondiabetic individuals: The HERITAGE Family Study. Diabetes 53:1603-1608, 2004
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124. Stanforth P, Jackson AS, Green JS, Gagnon J, Rankinen T, Despres J-P, Bouchard C, Leon AS, Rao DC, Skinner JS and Wilmore JH. Generalized abdominal visceral fat prediction models for black and white adults aged 17-65 y: The HERITAGE Family Study. International Journal of Obesity 28;925-932, 2004.
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125. Loos RJF, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC and Bouchard C. Calcium intake is associated with adiposity in black and white men and white women of the HERITAGE Family Study. Journal of Nutrition 134:1772-1778, 2004.
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126. Green JS, Stanforth PR, Rankinen T, Leon AS, Rao DC, Skinner JS, Bouchard C, Wilmore JH. The effects of exercise training on abdominal visceral fat, body composition, and indicators of the metabolic syndrome in postmenopausal women with and without estrogen replacement therapy: The HERITAGE Family Study. Metabolism 53:1192-1196, 2004.
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127. Ardern CI, Katzmarzyk PT, Janssen I, Leon AS, Wilmore JH, Skinner JS, Rao DC, Rankinen T, Despres JP, Rankinen T, Bouchard C. Race and sex similarities in exercise-induced changes in blood lipids and fatness. Medicine and Science in Sports and Exercise 36:1610-1615, 2004.
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2005


128. Boulé NG, Weisnagel SJ, Lakka TA, Tremblay A, Bergman RN, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. Effects of exercise training on glucose homeostasis: The HERITAGE Family Study. Diabetes Care 28:108-114, 2005.
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129. Feitosa MF, Borecki IB, Rankinen T, Rice T, Despres JP, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Bouchard C, Province MA, Rao DC. Evidence of QTLs on chromosomes 1q42 and 8q24 for LDL-cholesterol and apoB levels in the HERITAGE Family Study. Journal of Lipid Research 46:281-286, 2005
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130. Feitosa MF, Rice T, Rankinen T, Almasy L, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Common genetic and environmental effects on lipid phenotypes: The HERITAGE Family Study. Human Heredity 59:34-40, 2005
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131. Teran-Garcia M, Rankinen T, Koza RA, Rao DC, Bouchard C. Endurance training -induced changes in insulin sensitivity and gene expression. American Journal of Physiology - Endocrinology and Metabolism 288:E1168-78, 2005.
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132. Ukkola O, Rankinen T, Lakka T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Kesaniemi YA, Bouchard C. Protein tyrosine phosphatase 1B variant associated with fat distribution and insulin metabolism. Obesity Research 13:829-834, 2005
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133. Ukkola O, Santaniemi M, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Kesaniemi YA, Bouchard C. Adiponectin polymorphisms, adiposity and insulin metabolism: HERITAGE Family Study and Oulu Diabetic Study. Annals of Medicine 37:141-150, 2005.
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134. An P, Teran-Garcia M, Rice T, Rankinen T, Weisnagel SJ, Bergman RN, Boston RC, Mandel S, Stefanovski D, Leon AS, Skinner JS, Rao DC, Bouchard C. Genome-wide linkage scans for prediabetes phenotypes in response to 20 weeks of endurance exercise training in non-diabetic Whites and Blacks: The HERITAGE Family Study. Diabetologia 48:1142-1149, 2005.
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135. Teran-Garcia M, Santoro N, Rankinen T, Bergeron J, Rice T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Despres JP, Bouchard C. Hepatic lipase gene variant -514C>T variant is associated with lipoprotein and insulin sensitivity response to regular exercise: the HERITAGE Family Study. Diabetes 54;2251-2255, 2005.
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136. An P, Borecki IB, Rankinen T, Despres JP, Leon AS, Skinner JS, Wilmore JH, Bouchard C and Rao DC. Evidence of major genes for plasma HDL, LDL cholesterol and triglyceride levels at baseline and in response to 20 weeks of endurance training: the HERITAGE Family Study. International Journal of Sports Medicine 26;414-419, 2005
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137. Feitosa MF, Rice T, Rankinen T, Province MA, Chagnon YC, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Despres JP, Bouchard C, Rao DC, Borecki IB. Evidence of QTLs on chromosomes 13q and 14q for triglycerides before and after 20 weeks of exercise training: The HERITAGE Family Study. Atherosclerosis 182;349-360, 2005.
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138. Lakka TA, Lakka HM, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE Family Study. European Heart Journal 26;2018-2025, 2005.
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139. Loos RJF, Rankinen T, Rice T, Rao DC, Leon AS, Skinner JS, Wilmore JH, Argyropoulos G, Bouchard C. Two ethnic-specific polymorphisms in the Agouti-Related protein gene are associated with food intake in Whites and Blacks in the HERITAGE Family Study. American Journal of Clinical Nutrition 82:1097-1101, 2005
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2006

140. An P, Rice T, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. Genome-wide scan to identify quantitative trait loci for baseline resting heart rate and its response to endurance exercise training: The HERITAGE Family Study. International Journal of Sports Medicine 27:31-6, 2006
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141. Rice T, Cooper RS, Wu X, Bouchard C, Rankinen T, Rao DC, Jaquish CE, Fabsitz RR, Province MA. Meta-Analysis of Genome-Wide Scans for Blood Pressure in African American and Nigerian Samples. The National Heart, Lung, and Blood Institute GeneLink Project. Am J Hypertens. 19:270-4, 2006.
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142. Feitosa MF, Rice T, North KE, Kraja A, Rankinen T, Leon AS, Skinner JS, Blangero J, Bouchard C, Rao DC. Pleiotropic QTL on chromosome 19q13 for triglycerides and adiposity: the HERITAGE Family Study. Atherosclerosis 185:426-432, 2006.
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143. Lakka HM, Lakka TA, Rankinen T, Rice T, Rao DC, Leon AS, Skinner JS, Bouchard C. TNF-alpha G-308A polymorphism is associated with plasma C-reactive protein levels: the HERITAGE Family Study. Vascul Pharmacol 44:377-383, 2006.
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144. Okura T, Rankinen T, Gagnon J, Lussier-Cacan S, Davignon J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. Effect of regular exercise on plasma homocysteine concentrations: the HERITAGE Family Study. European Journal of Applied Physiology 98:394-401, 2006.
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145. Lakka TA, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Bouchard C. Quantitative trait locus on chromosome 20q13 for plasma levels of C-reactive protein in healthy whites: the HERITAGE Family Study. Physiological Genomics 27:103-107, 2006.
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146. Turley KR, Spears FM, Stanforth PR, Rankinen T, Bouchard C, Leon AS, Rao DC, Skinner JS and Wilmore JH. Scaling submaximal exercise cardiac output and stroke volume: The HERITAGE Family Study. International Journal of Sports Medicine 27:993-999, 2006.
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147. Feitosa MF, Rice T, Borecki IB, Rankinen T, Leon AS, Skinner JS, Després J-P, Blangero J, Bouchard C and Rao DC. Pleiotropic QTL on 12q23-q24 influences triglyceride and high density lipoprotein-cholesterol levels: the HERITAGE Family Study. Human Biology 78:317-327, 2006.
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2007

148. Blanche D, Lussier-Cacan S, Gagnon J, Leon AS, Rao DC, Skinner JS, Wilmore JH, Rankinen T, Bouchard C, Davignon J. Effect of exercise training on in vitro LDL oxidation and free radical-induced hemolysis: The HERITAGE Family Study. Antioxidants and Redox signaling 9:123-130, 2007.
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149. Hautala AJ, Leon AS, Skinner JS, Rao DC, Bouchard C, Rankinen T. Peroxisome proliferator-activated receptor delta polymorphisms are associated with physical performance and plasma lipids: the HERITAGE Family Study. American Journal of Physiology Heart and Circulatory Physiology 292:H2498-H2505, 2007.
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150. Teran-Garcia M, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Bouchard C. Variations in the four and a half LIM domain 1 gene (FHL1) are associated with fasting insulin and insulin sensitivity responses to regular exercise. Diabetologia 50:1858-66, 2007.
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151. Spielmann N, Leon AS, Rao DC, Rice T, Skinner JS, Bouchard C, Rankinen T. CETP genotypes and HDL-cholesterol phenotypes in the HERITAGE Family Study. Physiological Genomics 31:25-31, 2007.
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152. Rankinen T, Church T, Rice T, Markward N, Leon AS, Rao DC, Skinner JS, Blair SN and Bouchard C. Effect of endothelin 1 genotype on blood pressure is dependent on physical activity and fitness levels. Hypertension 50:1120-1125, 2007.
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153. Spielmann N, Leon AS, Rao DC, Rice T, Skinner JS, Rankinen T, Bouchard C. Genome-wide linkage scan for submaximal exercise heart rate in the HERITAGE Family Study. American Journal of Physiology Heart Circ Physiology 293:3366-3371, 2007.
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2009

154. Argyropoulos G, Stütz AM, Ilnytska O, Rice T, Teran-Garcia M, Rao DC, Bouchard C, Rankinen T. KIF5B gene sequence variation and response of cardiac stroke volume to regular exercise. Physiological Genomics 36:79-88, 2009.
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155. Stütz A, Teran-Garcia M, Rao DC, Rice T, Bouchard C, Rankinen T. Functional identification of the promoter of SLC4A5, a gene associated with cardiovascular and metabolic phenotypes in the HERITAGE Family Study. European Journal of Human Genetics 17:1481-1489, 2009.
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156. Heid IM, Huth C, Loos RJF, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Beibermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Frances F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries, Hunt SC, Illig T, Jarvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Völzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: Does heterogeneity of estimates relate to study design? Plos Genetics 2009;5(10):e1000694.
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2010

157. Rankinen T, Rice T, Teran-Garcia M, Rao DC, Bouchard C. FTO genotype is associated with exercise-induced changes in body composition: the HERITAGE Family Study. Obesity 18:322-326, 2010.
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158. Ruchat SM, Rankinen T, Weisnagel SJ, Rice T, Rao DC, Bergman RN, Bouchard C, Perusse L. Improvements in glucose homeostasis in response to regular exercise are influenced by PPARG Pro12Ala variant: Results from the HERITAGE Family Study. Diabetologia 53:679-689, 2010
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159. Timmons JA, Knudsen S, Rankinen T, Koch LG, Sarzynski M, Jensen T, Keller P, Scheele C, Vollaard NBJ, Nielsen S, Ĺkerström T, MacDougald OA, Jansson E, Greenhaff PL, Tarnopolsky MA, van Loon LJC, Pedersen BK, Sundberg CJ, Wahlestedt C, Britton SL, Bouchard C. Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. Journal of Applied Physiology 108:1487-1496, 2010
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160. Rankinen T, Argyropoulos G, Rice T, Rao DC, Bouchard C. CREB1 is a strong genetic predictor of the variation in exercise heart rate response to regular exercise: the HERITAGE Family Study. Circulation: Cardiovascular Genetics 3:294-299, 2010
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2011

161. Keller P, Vollaard NBJ, Gustafsson T, Gallagher IJ, Sundberg CJ, Rankinen T, Britton SL, Bouchard C, Koch LG Timmons JA. A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype. Journal of Applied Physiology 110:46-59, 2011.
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162. Krishnapuram R, Dhurandhar EJ, Dubuisson O, Kirk-Ballard H, Bajpeyi S, Butte N, Sothern MS, Larsen-Meyer E, Chalew S, Bennett B, Gupta AK, Greenway FL, Johnson W, Brashear M, Reinhart G, Rankinen T, Bouchard C, Cefalu WT, Ye J, Javier R, Zuberi A, Dhurandhar NV. Template to Improve Glycemic Control without Reducing Adiposity or Dietary Fat. American Journal of Physiology - Endocrinology and Metabolism 300:E779-89, 2011
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163. Bouchard C, Sarzynski MA, Rice T, Kraus W, Church T, Sung YJ, Rao DC, Rankinen T. Genomic predictors of maximal O2 uptake response to standardized exercise training programs. Journal of Applied Physiology 110:1160-1170, 2011
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2012

164. Sung YJ, Wang L, Rankinen T, Bouchard C, Rao DC. Performance of genotype imputations using data from the 1000 genomes project. Human Heredity 73:18-25, 2012.
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165. Rankinen T, Sung YJ, Sarzynski M, Rao DC, Bouchard C. The heritability of submaximal exercise heart rate response to exercise training is accounted for by nine SNPs. Journal of Applied Physiology 112:892-897, 2012.
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166. Bouchard C, Blair SN, Church TS, Earnest CP, Hagberg JM, Häkkinen K, Jenkins NT, Karavirta L, Kraus WE, Leon AS, Rao DC, Sarzynski MA, Skinner JS, Slentz C, Rankinen T. Adverse metabolic response to regular exercise: Is it a rare or common occurrence? PLoS ONE 7(5): e37887.
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167. Rice TK, Sarzynski MA, Sung YJ, Argyropoulos G, Stütz AM, Teran-Garcia M, Rao DC, Bouchard C, Rankinen T. Fine mapping of a QTL on chromosome 13 for submaximal exercise capacity training response: the HERITAGE Family Study. European Journal of Applied Physiology 112:2969-2978, 2012.
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2013

168.  Phillips BE, Williams JP, Gustafsson T, Bouchard C, Rankinen T, Knudsen S, Smith K, Timmons JA, Atherton PJ. Molecular networks of human muscle adaptation to exercise and age. PLoS Genetics 9:e1003389, 2013
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170. Sarzynski MA, Rankinen T, Earnest C, Leon AS, Rao DC, Skinner JM, Bouchard C. Measured maximal heart rates compared to commonly used age-based prediction equations in the HERITAGE Family Study. American Journal of Human Biology 25:695-701, 2013
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2014

172. Roberts LD, Boström P, O’Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee Y-K, Palma MJ, Calhoun S, Georgiadi A, Chen M-H, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE. Beta-Aminoisobutyric acid induces browning of white fat and hepatic beta-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metabolism 19:96-108, 2014
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