Study Type


Study Purpose

Obesity is now viewed as a complex disease, resistant to many forms of treatment. Obesity can lead to increased risk for type 2 diabetes, therefore, there is a need for medications that both help lower blood sugar levels and lead to significant weight loss in an effort to help slow down or even reverse type 2 diabetes.

The BEGIN research study will assess the effectiveness of a study drug for the potential management of type 2 diabetes. Researchers will also evaluate if the study drug is able to reduce weight in patients with type 2 diabetes.

About the Study

The study consists of 17 total visits to the Pennington Biomedical Clinic. These visits will take place over a period of approximately 1 year and 2 months.

Participants will continue their regular diabetes treatment throughout this study and will receive diet and exercise counseling on a regular basis.

Study Design

Number of Visits:

  • 1 screening visit
  • 17 study visits
  • 12 phone calls


  • Medical history
  • Vital signs (pulse and blood pressure)
  • Physical exam (Height, weight, etc.)
  • Electrocardiogram (EKG)
  • DXA Scan
  • MRI (optional)
  • Meal Test
  • Physical performance tests
  • Pregnancy tests
  • Blood tests
  • Questionnaires

Study Qualifications

To qualify for this research study, participants should:

  • Be 18 to 75 years of age
  • Be diagnosed with type 2 diabetes
  • Have a BMI between 28 – 40 calculate your BMI
  • Have a body weight of 143 – 308 pounds
  • Not be pregnant

Study Duration

Participation in this research study will last approximately 1 year and 2 months.


Compensation of up to $1000 is offered for completion of this study.

Study Contact

If you are interested in volunteering for this research study, click here to screen online, call 225-763-3000 or email

If you think you may be eligible, please click the button below to screen online.


Please do not fill out this questionnaire for anyone other than yourself unless you are their legal guardian.
If you know someone who may be interested please direct them to the site or have them call us directly at 225-763-3000.


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