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PBRC NEWS |
Genes reveal how much we will benefit from regular exercise
Thursday, February 04, 2010
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Medical therapy delivered by primary care doctors is successful in severe obesity
Monday, January 25, 2010
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Can exercise keep a spring in our step longer?
Wednesday, November 04, 2009
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A decade later, lifestyle changes continue to lower type 2 diabetes risk
Wednesday, October 28, 2009
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Scientists launch statewide dementia research program
Public invited to “Meet the Experts”
Tuesday, October 27, 2009
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Experts grade children’s health;
Louisiana gets a “D” – again
Monday, September 14, 2009
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TAKE 5 FOR DIABETES |
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Pennington Biomedical Research Center’s Take 5 for Diabetes Education Program is a series of 5 class meetings designed for individuals with Type II diabetes, metabolic syndrome, pre-diabetes or those who have a family history of diabetes. To learn more, click here. |
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Elizabeth Floyd, Ph.D.
Assistant Professor - Research
Department/Laboratory:
Ubiquitin Lab
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Phone:
(225) 763-2724
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Fax:
(225) 763-0273 |
Send
E-mail
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Education:
Ph.D., Louisiana State University, Baton Rouge, LA, 1997, Biochemistry
B.S., Univesity of Alabama at Birmingham, Birmingham, AL, 1977, Nursing
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Research
Interests:
Dr. Floyd has a general interest in protein turnover mediated by the ubiquitin-proteasome system. In particular, she is interested in understanding how the ubiquitin-proteasome pathway affects the activity of nuclear proteins such as transcription factors. Her research is currently focused on how ubiquitin and ubiquitin-like modifications regulate the activity of the peroxisome proliferator-activated receptor gamma (PPARg), a nuclear hormone receptor required for the formation of adipocytes.
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Selected
Publications:
Floyd ZE, Stephens JM. Control of peroxisome proliferator-activated receptor gamma2 stability and activity by SUMOylation. Obes Res. 2004 Jun;12(6):921-8.
Floyd ZE, Stephens JM. STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid receptor during adipocyte differentiation. Diabetes. 2003 Feb;52(2):308-14
Floyd ZE, Stephens JM. Chapter 3: STAT5A promotes adipogenesis in nonprecursor cells. In Proceedings of Progress in Obesity 9, G Medeiros-Neto, A Halpern and C Bouchard, eds. John Libbey, Eurotext, 2003
Floyd, Z.E. and Stephens, J.M. (2002) IFN gamma-mediated activation and ubiquitin-proteasome dependent degradation of PPAR gamma in adipocytes. J. Biol. Chem. 277, 4062-4068.
Waite, K.J., Floyd, Z.E., Arbour-Riley, P., Stephens, J.M. (2001) Interferon-gamma-induced regulation of peroxisome proliferator-activated receptor gamma and STATs in adipocytes. J. Biol. Chem. 276, 7062-7068.
Floyd, Z.E., Trausch-Azar, J.S., Reinstein, E., Ciechanover, A., Schwartz, A.L. (2001) The Nuclear Ubiquitin-Proteasome System Degrades MyoD. J. Biol. Chem. 276, 22468-22475.
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